Microhomology-mediated circular DNA formation from oligonucleosomal fragments during spermatogenesis

The landscape of extrachromosomal circular DNA (eccDNA) during mammalian spermatogenesis, as well as the biogenesis mechanism, remains to be explored. Here, we revealed widespread eccDNA formation in human sperms and mouse spermatogenesis. We noted that germline eccDNAs are derived from oligonucleos...

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Detalles Bibliográficos
Autores principales: Hu, Jun, Zhang, Zhe, Xiao, Sai, Cao, Yalei, Chen, Yinghong, Weng, Jiaming, Jiang, Hui, Li, Wei, Chen, Jia-Yu, Liu, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10581685/
https://www.ncbi.nlm.nih.gov/pubmed/37847146
http://dx.doi.org/10.7554/eLife.87115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10581685/
https://www.ncbi.nlm.nih.gov/pubmed/37847146
http://dx.doi.org/10.7554/eLife.87115

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