Impaired cognitive and motor function are coincident with l-DOPA-induced dyskinesia in a model of Parkinson’s disease

Dopamine transmission has been implicated in motor and cognitive function. In Parkinson’s disease (PD), dopamine replacement using the precursor drug l-DOPA is the predominant treatment approach, but long-term exposure leads to the onset of dyskinesias (LIDs). Chronic l-DOPA exposure has been associ...

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Detalles Bibliográficos
Autores principales: Lelos, Mariah J., Murphy, Ellen M., Lindgren, Hanna S., Dunnett, Stephen B., Lane, Emma L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10582029/
https://www.ncbi.nlm.nih.gov/pubmed/37848479
http://dx.doi.org/10.1038/s41598-023-44869-y

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