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Endogenous renal adiponectin drives gluconeogenesis through enhancing pyruvate and fatty acid utilization
Adiponectin is a secretory protein, primarily produced in adipocytes. However, low but detectable expression of adiponectin can be observed in cell types beyond adipocytes, particularly in kidney tubular cells, but its local renal role is unknown. We assessed the impact of renal adiponectin by utili...
Autores principales: | Onodera, Toshiharu, Wang, May-Yun, Rutkowski, Joseph M., Deja, Stanislaw, Chen, Shiuhwei, Balzer, Michael S., Kim, Dae-Seok, Sun, Xuenan, An, Yu A., Field, Bianca C., Lee, Charlotte, Matsuo, Ei-ichi, Mizerska, Monika, Sanjana, Ina, Fujiwara, Naoto, Kusminski, Christine M., Gordillo, Ruth, Gautron, Laurent, Marciano, Denise K., Hu, Ming Chang, Burgess, Shawn C., Susztak, Katalin, Moe, Orson W., Scherer, Philipp E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10582045/ https://www.ncbi.nlm.nih.gov/pubmed/37848446 http://dx.doi.org/10.1038/s41467-023-42188-4 |
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