Cargando…

Genome-wide meta-analysis of 92 cardiometabolic protein serum levels

OBJECTIVES: Global cardiometabolic disease prevalence has grown rapidly over the years, making it the leading cause of death worldwide. Proteins are crucial components in biological pathways dysregulated in disease states. Identifying genetic components that influence circulating protein levels may...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gilly, Arthur, Park, Young-Chan, Tsafantakis, Emmanouil, Karaleftheri, Maria, Dedoussis, George, Zeggini, Eleftheria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10582065/ https://www.ncbi.nlm.nih.gov/pubmed/37778719 http://dx.doi.org/10.1016/j.molmet.2023.101810

Ejemplares similares

Whole-genome sequencing analysis of the cardiometabolic proteome
por: Gilly, Arthur, et al.
Publicado: (2020)

Population‐wide copy number variation calling using variant call format files from 6,898 individuals
por: Png, Grace, et al.
Publicado: (2019)

Gene-based whole genome sequencing meta-analysis of 250 circulating proteins in three isolated European populations
por: Gilly, Arthur, et al.
Publicado: (2022)

Very low-depth sequencing in a founder population identifies a cardioprotective APOC3 signal missed by genome-wide imputation
por: Gilly, Arthur, et al.
Publicado: (2016)

Proteomic analysis of 92 circulating proteins and their effects in cardiometabolic diseases
por: Carland, Corinne, et al.
Publicado: (2023)

Identifying causal serum protein–cardiometabolic trait relationships using whole genome sequencing
por: Png, Grace, et al.
Publicado: (2022)

Mapping the serum proteome to neurological diseases using whole genome sequencing
por: Png, Grace, et al.
Publicado: (2021)

Whole genome sequencing and imputation in isolated populations identify genetic associations with medically-relevant complex traits
por: Southam, Lorraine, et al.
Publicado: (2017)

A Dietary Pattern with High Sugar Content Is Associated with Cardiometabolic Risk Factors in the Pomak Population
por: Farmaki, Aliki-Eleni, et al.
Publicado: (2019)

Insights into the genetic architecture of haematological traits from deep phenotyping and whole-genome sequencing for two Mediterranean isolated populations
por: Kuchenbaecker, Karoline, et al.
Publicado: (2022)

Cohort-wide deep whole genome sequencing and the allelic architecture of complex traits
por: Gilly, Arthur, et al.
Publicado: (2018)

Very low-depth whole-genome sequencing in complex trait association studies
por: Gilly, Arthur, et al.
Publicado: (2019)

Author Correction: Cohort-wide deep whole genome sequencing and the allelic architecture of complex traits
por: Gilly, Arthur, et al.
Publicado: (2018)

The transferability of lipid loci across African, Asian and European cohorts
por: Kuchenbaecker, Karoline, et al.
Publicado: (2019)

Bridging the diversity gap: Analytical and study design considerations for improving the accuracy of trans-ancestry genetic prediction
por: Bocher, Ozvan, et al.
Publicado: (2023)

Using population isolates in genetic association studies
por: Hatzikotoulas, Konstantinos, et al.
Publicado: (2014)

Genetic characterization of Greek population isolates reveals strong genetic drift at missense and trait-associated variants
por: Panoutsopoulou, Kalliope, et al.
Publicado: (2014)

Synthetic associations in the context of genome-wide association scan signals
por: Orozco, Gisela, et al.
Publicado: (2010)

Synthetic Associations Are Unlikely to Account for Many Common Disease Genome-Wide Association Signals
por: Anderson, Carl A., et al.
Publicado: (2011)

Estimating Genome-Wide Significance for Whole-Genome Sequencing Studies
por: Xu, ChangJiang, et al.
Publicado: (2014)

Replication of Established Common Genetic Variants for Adult BMI and Childhood Obesity in Greek Adolescents: The TEENAGE Study
por: Ntalla, Ioanna, et al.
Publicado: (2013)

Using genetically isolated populations to understand the genomic basis of disease
por: Zeggini, Eleftheria
Publicado: (2014)

Serum Adiponectin Levels and Their Association With Cardiometabolic Risk Factors in Patients With Psoriasis
por: Chan, Wai Sze Agnes, et al.
Publicado: (2020)

The role of cardiometabolic risk factors and endothelial dysfunction in serum albumin levels of patients with COVID-19
por: Oikonomou, Evangelos, et al.
Publicado: (2022)

Genome-Wide Association Analysis of Imputed Rare Variants: Application to Seven Common Complex Diseases
por: Mägi, Reedik, et al.
Publicado: (2012)

Functional genomics in osteoarthritis: Past, present, and future
por: Steinberg, Julia, et al.
Publicado: (2016)

Associations of VEGF-A-Related Variants with Adolescent Cardiometabolic and Dietary Parameters
por: Kafyra, Maria, et al.
Publicado: (2023)

PS92. Serum BDNF and GDNF levels before and after the 12-week antidepressant treatments among outpatients with major depressive disorder
por: Lee, Bun-Hee, et al.
Publicado: (2016)

Mendelian Randomization Analysis Reveals a Causal Influence of Circulating Sclerostin Levels on Bone Mineral Density and Fractures
por: Zheng, Jie, et al.
Publicado: (2019)

Genome-wide analyses using UK Biobank data provide insights into the genetic architecture of osteoarthritis
por: Zengini, Eleni, et al.
Publicado: (2018)

GLIDERS - A web-based search engine for genome-wide linkage disequilibrium between HapMap SNPs
por: Lawrence, Robert, et al.
Publicado: (2009)

Genome-Wide Association Analysis of Eating Disorder-Related Symptoms, Behaviors, and Personality Traits
por: Boraska, Vesna, et al.
Publicado: (2012)

Genome-wide genotype-serum proteome mapping provides insights into the cross-ancestry differences in cardiometabolic disease susceptibility
por: Xu, Fengzhe, et al.
Publicado: (2023)

A rare functional cardioprotective APOC3 variant has risen in frequency in distinct population isolates
por: Tachmazidou, Ioanna, et al.
Publicado: (2013)

Effects of chronic cobalt and chromium exposure after metal‐on‐metal hip resurfacing: An epigenome‐wide association pilot study
por: Steinberg, Julia, et al.
Publicado: (2017)

Correlation Between Serum AMH Levels and Cardiometabolic Indices in PCOS Women
por: Mitra, Subarna, et al.
Publicado: (2021)

Interrogating Type 2 Diabetes Genome-Wide Association Data Using a Biological Pathway-Based Approach
por: Perry, John R.B., et al.
Publicado: (2009)

EXM 92-16: 27/08/92
por: Daems, G
Publicado: (1992)

EXM 92-01 18/03/92
por: Daems, G
Publicado: (1992)

EXM 92-02 26/03/92
por: Daems, G
Publicado: (1992)

Cannot write session to /tmp/vufind_sessions/sess_1ckkkce696ahels5d1b117jnvh