Multi-ancestry epigenome-wide analyses identify methylated sites associated with aortic augmentation index in TOPMed MESA

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Despite the prognostic value of arterial stiffness (AS) and pulsatile hemodynamics (PH) for cardiovascular morbidity and mortality, epigenetic modifications that contribute to AS/PH remain unknown. To gain a better understanding of the link between epigenetics (DNA methylation) and AS/PH, we examine...

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Detalles Bibliográficos
Autores principales: Hu, Xiaowei, Logan, Jeongok G., Kwon, Younghoon, Lima, Joao A. C., Jacobs, David R., Duprez, Daniel, Brumback, Lyndia, Taylor, Kent D., Durda, Peter, Johnson, W. Craig, Cornell, Elaine, Guo, Xiuqing, Liu, Yongmei, Tracy, Russell P., Blackwell, Thomas W., Papanicolaou, George, Mitchell, Gary F., Rich, Stephen S., Rotter, Jerome I., Van Den Berg, David J., Chirinos, Julio A., Hughes, Timothy M., Garrett-Bakelman, Francine E., Manichaikul, Ani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10582077/
https://www.ncbi.nlm.nih.gov/pubmed/37848499
http://dx.doi.org/10.1038/s41598-023-44806-z

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