Phagocytosis-initiated tumor hybrid cells acquire a c-Myc-mediated quasi-polarization state for immunoevasion and distant dissemination

While macrophage phagocytosis is an immune defense mechanism against invading cellular organisms, cancer cells expressing the CD47 ligand send forward signals to repel this engulfment. Here we report that the reverse signaling using CD47 as a receptor additionally enhances a pro-survival function of...

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Detalles Bibliográficos
Autores principales: Chou, Chih-Wei, Hung, Chia-Nung, Chiu, Cheryl Hsiang-Ling, Tan, Xi, Chen, Meizhen, Chen, Chien-Chin, Saeed, Moawiz, Hsu, Che-Wei, Liss, Michael A., Wang, Chiou-Miin, Lai, Zhao, Alvarez, Nathaniel, Osmulski, Pawel A., Gaczynska, Maria E., Lin, Li-Ling, Ortega, Veronica, Kirma, Nameer B., Xu, Kexin, Liu, Zhijie, Kumar, Addanki P., Taverna, Josephine A., Velagaleti, Gopalrao V. N., Chen, Chun-Liang, Zhang, Zhao, Huang, Tim Hui-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10582093/
https://www.ncbi.nlm.nih.gov/pubmed/37848444
http://dx.doi.org/10.1038/s41467-023-42303-5

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