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Appearance and recurrence of odontogenic keratocysts

OBJECTIVE: The purpose of this study was to evaluate the appearance, histopathological features, and recurrence of odontogenic keratocysts (OKCs) from a large single institute registry over a 36‐year period. MATERIALS AND METHODS: A total of 226 cases of OKC were identified in 174 patients over a 36...

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Autores principales: Pylkkö, Jaakko, Willberg, Jaana, Suominen, Auli, Laine, Hanna K., Rautava, Jaana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10582210/
https://www.ncbi.nlm.nih.gov/pubmed/37794837
http://dx.doi.org/10.1002/cre2.796
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author Pylkkö, Jaakko
Willberg, Jaana
Suominen, Auli
Laine, Hanna K.
Rautava, Jaana
author_facet Pylkkö, Jaakko
Willberg, Jaana
Suominen, Auli
Laine, Hanna K.
Rautava, Jaana
author_sort Pylkkö, Jaakko
collection PubMed
description OBJECTIVE: The purpose of this study was to evaluate the appearance, histopathological features, and recurrence of odontogenic keratocysts (OKCs) from a large single institute registry over a 36‐year period. MATERIALS AND METHODS: A total of 226 cases of OKC were identified in 174 patients over a 36‐year period in a single institute in Southwestern Finland. Histological specimens were re‐evaluated. The patient's age, sex, location, recurrence, and histopathological features of the OKC were the study variables. RESULTS: OKCs occurred more frequently in men, the mean age was 46 years, and the most frequent site was the lower jaw. Recurrence rate was 21%. Histopathologically, inflammation was present in 95% and satellite cysts in 10% of cases. In patients diagnosed with satellite cysts, OKC recurred in 50% of cases, while the corresponding figure for patients without satellite cysts was 17%. CONCLUSIONS: Compared with the literature, patients were older and inflamed cysts were found more frequently. Satellite cysts occurred only in association with chronic inflammation. Based on the results, regular radiographic evaluation is important among patients aged 10–29 years to detect OKCs and to treat them before enlargement, infection, and inflammation. Satellite cysts should be reported and may be a sign of increased risk of OKC recurrence.
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spelling pubmed-105822102023-10-19 Appearance and recurrence of odontogenic keratocysts Pylkkö, Jaakko Willberg, Jaana Suominen, Auli Laine, Hanna K. Rautava, Jaana Clin Exp Dent Res Original Articles OBJECTIVE: The purpose of this study was to evaluate the appearance, histopathological features, and recurrence of odontogenic keratocysts (OKCs) from a large single institute registry over a 36‐year period. MATERIALS AND METHODS: A total of 226 cases of OKC were identified in 174 patients over a 36‐year period in a single institute in Southwestern Finland. Histological specimens were re‐evaluated. The patient's age, sex, location, recurrence, and histopathological features of the OKC were the study variables. RESULTS: OKCs occurred more frequently in men, the mean age was 46 years, and the most frequent site was the lower jaw. Recurrence rate was 21%. Histopathologically, inflammation was present in 95% and satellite cysts in 10% of cases. In patients diagnosed with satellite cysts, OKC recurred in 50% of cases, while the corresponding figure for patients without satellite cysts was 17%. CONCLUSIONS: Compared with the literature, patients were older and inflamed cysts were found more frequently. Satellite cysts occurred only in association with chronic inflammation. Based on the results, regular radiographic evaluation is important among patients aged 10–29 years to detect OKCs and to treat them before enlargement, infection, and inflammation. Satellite cysts should be reported and may be a sign of increased risk of OKC recurrence. John Wiley and Sons Inc. 2023-10-05 /pmc/articles/PMC10582210/ /pubmed/37794837 http://dx.doi.org/10.1002/cre2.796 Text en © 2023 The Authors. Clinical and Experimental Dental Research published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Pylkkö, Jaakko
Willberg, Jaana
Suominen, Auli
Laine, Hanna K.
Rautava, Jaana
Appearance and recurrence of odontogenic keratocysts
title Appearance and recurrence of odontogenic keratocysts
title_full Appearance and recurrence of odontogenic keratocysts
title_fullStr Appearance and recurrence of odontogenic keratocysts
title_full_unstemmed Appearance and recurrence of odontogenic keratocysts
title_short Appearance and recurrence of odontogenic keratocysts
title_sort appearance and recurrence of odontogenic keratocysts
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10582210/
https://www.ncbi.nlm.nih.gov/pubmed/37794837
http://dx.doi.org/10.1002/cre2.796
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