YIV-818-A: a novel therapeutic agent in prostate cancer management through androgen receptor downregulation, glucocorticoid receptor inhibition, epigenetic regulation, and enhancement of apalutamide, darolutamide, and enzalutamide efficacy

Introduction: Prostate cancer is the second leading cause of cancer death among men in the United States. Castration-Resistant Prostate Cancer (CRPC) often develops resistance to androgen deprivation therapy. Resistance in CRPC is often driven by AR variants and glucocorticoid receptor (GR). Thus, d...

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Detalles Bibliográficos
Autores principales: Lam, Wing, Arammash, Mohammad, Cai, Wei, Guan, Fulan, Jiang, Zaoli, Liu, Shwu-Huey, Cheng, Peikwen, Cheng, Yung-Chi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10582333/
https://www.ncbi.nlm.nih.gov/pubmed/37860121
http://dx.doi.org/10.3389/fphar.2023.1244655

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