Topical Drug Delivery of Concentrated Cabazitaxel in an α‐Tocopherol and DMSO Solution

Topical chemotherapy approaches are relevant for certain skin cancer treatments. This study observes that cabazitaxel (CTX), a broad‐spectrum second‐generation taxane cytotoxic agent, can be dissolved in α‐tocopherol at high concentrations exceeding 100 mg mL(−1). 2D nuclear magnetic resonance (NMR)...

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Detalles Bibliográficos
Autores principales: Sun, Boyang, Paraskevopoulos, Georgios, Min, Jiwei, Rossdeutcher, Robert, Ghosh, Sanjana, Quinn, Breandan, Lin, Meng‐Hsuan, Sarkar, Debanjan, Sukumaran, Dinesh, Wang, Yuefei, Vávrová, Kateřina, Lovell, Jonathan F., Zhang, Yumiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10582425/
https://www.ncbi.nlm.nih.gov/pubmed/37555802
http://dx.doi.org/10.1002/advs.202302658

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