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PGAM1 Inhibition Promotes HCC Ferroptosis and Synergizes with Anti‐PD‐1 Immunotherapy

The combination of immunotherapy and molecular targeted therapy exhibits promising therapeutic efficacy in hepatocellular carcinoma (HCC), but the underlying mechanism is still unclear. Here, phosphoglycerate mutase 1 (PGAM1) is identified as a novel immunometabolic target by using a bioinformatic a...

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Detalles Bibliográficos
Autores principales: Zheng, Yimin, Wang, Yining, Lu, Zhou, Wan, Jinkai, Jiang, Lulu, Song, Danjun, Wei, Chuanyuan, Gao, Chao, Shi, Guoming, Zhou, Jian, Fan, Jia, Ke, Aiwu, Zhou, Lu, Cai, Jiabin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10582428/
https://www.ncbi.nlm.nih.gov/pubmed/37705495
http://dx.doi.org/10.1002/advs.202301928