Ventilatory efficiency (η⩒E) of the exercise: A detailed method report

Ventilatory efficiency is a combination of the ventilatory-metabolic response stemming from non-invasive analysis of cardiopulmonary exercise testing. Despite being a recognized marker in exercise physiology, this measure presents considerable limitations, including the imprecise designation of “efficiency”, broadly recognized, and recently denominated as “excess ventilation”. Herein we present a detailed method, with substantial improvements, and new physiological insights, in order to better define the true ventilatory efficiency of the exercise, according to recommendations for physical/physiological processes. • “Ventilatory efficiency” of the exercise is a remarkable physiological index. • Several limitations are currently debated. • We report a new ventilatory efficiency index that match with recommendations.