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Metformin inhibits inflammatory response and endoplasmic reticulum stress to improve hypothalamic aging in obese mice

The hypothalamus, as a vital brain region for endocrine and metabolism regulation, undergoes functional disruption during obesity.The anti-aging effect of metformin has come into focus. However, whether it has the potential to ameliorate hypothalamic aging and dysfunction in the obese state remains...

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Detalles Bibliográficos
Autores principales:	Yang, Leilei, Lu, Peng, Qi, Xiangyu, Yang, Qian, Liu, Luna, Dou, Tao, Guan, Qingbo, Yu, Chunxiao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10582490/ https://www.ncbi.nlm.nih.gov/pubmed/37860765 http://dx.doi.org/10.1016/j.isci.2023.108082

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