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Clinicopathological Characteristics of NRG1 Fusion–Positive Solid Tumors in Korean Patients

PURPOSE: Neuregulin 1 (NRG1) gene fusion is a potentially actionable oncogenic driver. The oncoprotein binds to ERBB3-ERBB2 heterodimers and activates downstream signaling, supporting a therapeutic approach for inhibiting ERBB3/ERBB2. However, the frequency and clinicopathological features of solid...

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Detalles Bibliográficos
Autores principales: Cha, Yoon Jin, Lee, Chung, Joo, Bio, Kim, Kyung A, Lee, Choong-kun, Shim, Hyo Sup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Cancer Association 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10582527/
https://www.ncbi.nlm.nih.gov/pubmed/37321274
http://dx.doi.org/10.4143/crt.2023.682