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Potassium canrenoate in brain-dead organ donors: a randomised controlled clinical trial protocol (CANREO-PMO)

INTRODUCTION: Ischaemia/reperfusion injuries (IRIs) are associated with poorer survival of kidney grafts from expanded criteria donors. Preclinical studies have shown that mineralocorticoid receptor antagonists (MRAs) prevent acute and chronic post-ischaemic renal dysfunction by limiting IRI. Howeve...

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Detalles Bibliográficos
Autores principales: Belarif, Lilia, Girerd, Sophie, Jaisser, Frédéric, Lepage, Xavier, Merckle, Ludovic, Duarte, Kevin, Girerd, Nicolas, Guerci, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10582869/
https://www.ncbi.nlm.nih.gov/pubmed/37821131
http://dx.doi.org/10.1136/bmjopen-2023-073831