Cargando…

Potassium canrenoate in brain-dead organ donors: a randomised controlled clinical trial protocol (CANREO-PMO)

INTRODUCTION: Ischaemia/reperfusion injuries (IRIs) are associated with poorer survival of kidney grafts from expanded criteria donors. Preclinical studies have shown that mineralocorticoid receptor antagonists (MRAs) prevent acute and chronic post-ischaemic renal dysfunction by limiting IRI. Howeve...

Descripción completa

Detalles Bibliográficos
Autores principales:	Belarif, Lilia, Girerd, Sophie, Jaisser, Frédéric, Lepage, Xavier, Merckle, Ludovic, Duarte, Kevin, Girerd, Nicolas, Guerci, Philippe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2023
Materias:	Intensive Care
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10582869/ https://www.ncbi.nlm.nih.gov/pubmed/37821131 http://dx.doi.org/10.1136/bmjopen-2023-073831

Ejemplares similares

Protocol for a multicentre randomised controlled trial evaluating the effects of moderate hypothermia versus normothermia on mortality in patients with refractory cardiogenic shock rescued by venoarterial extracorporeal membrane oxygenation (VA-ECMO) (HYPO-ECMO study)
por: Jacquot, Audrey, et al.
Publicado: (2019)

Ultrasound-guided versus landmark approach for peripheral intravenous access by critical care nurses: a randomised controlled study
por: Bridey, Céline, et al.
Publicado: (2018)

DONORS (Donation Network to Optimise Organ Recovery Study): Study protocol to evaluate the implementation of an evidence-based checklist for brain-dead potential organ donor management in intensive care units, a cluster randomised trial
por: Westphal, Glauco Adrieno, et al.
Publicado: (2019)

EPURE Transplant (Eplerenone in Patients Undergoing Renal Transplant) study: study protocol for a randomized controlled trial
por: Girerd, Sophie, et al.
Publicado: (2018)

Impact of targeted hypothermia in expanded-criteria organ donors on recipient kidney-graft function: study protocol for a multicentre randomised controlled trial (HYPOREME)
por: Brulé, Noëlle, et al.
Publicado: (2022)

Canada-DONATE study protocol: a prospective national observational study of the medical management of deceased organ donors
por: D’Aragon, Frederick, et al.
Publicado: (2017)

Effect of corticosteroid administration on neurologically deceased organ donors and transplant recipients: a systematic review and meta-analysis
por: D'Aragon, Frédérick, et al.
Publicado: (2017)

Comparison of Enteral versus Intravenous Potassium Supplementation in hypokalaemia in postcardiac surgery paediatric cardiac intensive care patients: prospective open label randomised control trial (EIPS)
por: Merchant, Quratulain, et al.
Publicado: (2014)

Patient-centred and family-centred care of critically ill patients who are potential organ donors: a qualitative study protocol of family member perspectives
por: Zheng, Katina, et al.
Publicado: (2020)

Epidural analgesia in critically ill patients with acute pancreatitis: the multicentre randomised controlled EPIPAN study protocol
por: Bulyez, Stéphanie, et al.
Publicado: (2017)

Use of glucose for pain management in premature neonates: a systematic review and meta-analysis protocol
por: Oliveira, Débora Joyce Duarte, et al.
Publicado: (2021)

Which spontaneous breathing trial to predict effort to breathe after extubation according to five critical illnesses: the cross-over GLOBAL WEAN study protocol
por: Capdevila, Mathieu, et al.
Publicado: (2023)

Fibrinolytic therapy in patients with COVID-19 and ARDS: protocol for a systematic review and meta-analysis
por: Savioli, Felicio, et al.
Publicado: (2023)

Haemodynamic response to crystalloids or colloids in shock: an exploratory subgroup analysis of a randomised controlled trial
por: Heming, Nicholas, et al.
Publicado: (2017)

Rapid rEcognition of COrticosteRoiD resistant or sensitive Sepsis (RECORDS): study protocol for a multicentre, placebo-controlled, biomarker-guided, adaptive Bayesian design basket trial
por: Fleuriet, Jérôme, et al.
Publicado: (2023)

High-flow nasal oxygen therapy alone or with non-invasive ventilation in immunocompromised patients admitted to ICU for acute hypoxemic respiratory failure: the randomised multicentre controlled FLORALI-IM protocol
por: Coudroy, Rémi, et al.
Publicado: (2019)

Haemoglobin transfusion threshold in traumatic brain injury optimisation (HEMOTION): a multicentre, randomised, clinical trial protocol
por: Turgeon, Alexis F, et al.
Publicado: (2022)

Study protocol to assess the effectiveness and safety of a flexible family visitation model for delirium prevention in adult intensive care units: a cluster-randomised, crossover trial (The ICU Visits Study)
por: Rosa, Regis Goulart, et al.
Publicado: (2018)

Metabolic Syndrome and the Risk of Preclinical Heart Failure: Insights after 17 Years of Follow-Up from the STANISLAS Cohort
por: Sharma, Abhinav, et al.
Publicado: (2022)

Impact of early low-calorie low-protein versus standard-calorie standard-protein feeding on outcomes of ventilated adults with shock: design and conduct of a randomised, controlled, multicentre, open-label, parallel-group trial (NUTRIREA-3)
por: Reignier, Jean, et al.
Publicado: (2021)

Interrogating a clinical database to study treatment of hypotension in the critically ill
por: Lee, Joon, et al.
Publicado: (2012)

Protocol: inspiratory muscle training for promoting recovery and outcomes in ventilated patients (IMPROVe): a randomised controlled trial
por: Bissett, Bernie M, et al.
Publicado: (2012)

Effect of intravenous GLutamine supplementation IN Trauma patients receiving enteral nutrition study protocol (GLINT Study): a prospective, blinded, randomised, placebo-controlled clinical trial
por: Al Balushi, Ruqaiya M, et al.
Publicado: (2011)

Accuracy of LightCycler® SeptiFast for the detection and identification of pathogens in the blood of patients with suspected sepsis: a systematic review protocol
por: Dark, Paul, et al.
Publicado: (2012)

A longitudinal qualitative exploration of healthcare and informal support needs among survivors of critical illness: the RELINQUISH protocol
por: Ramsay, Pam, et al.
Publicado: (2012)

A randomised controlled trial evaluating a rehabilitation complex intervention for patients following intensive care discharge: the RECOVER study
por: Walsh, Timothy Simon, et al.
Publicado: (2012)

Relevance of anxiety in clinical practice of Guillain-Barré syndrome: a cohort study
por: Sharshar, Tarek, et al.
Publicado: (2012)

Early rehabilitation in critical care (eRiCC): functional electrical stimulation with cycling protocol for a randomised controlled trial
por: Parry, Selina M, et al.
Publicado: (2012)

Procalcitonin levels to guide antibiotic therapy in adults with non-microbiologically proven apparent severe sepsis: a randomised controlled trial
por: Annane, Djillali, et al.
Publicado: (2013)

Adverse drug events in a paediatric intensive care unit: a prospective cohort
por: Silva, Dafne C B, et al.
Publicado: (2013)

A UK survey of rehabilitation following critical illness: implementation of NICE Clinical Guidance 83 (CG83) following hospital discharge
por: Connolly, Bronwen, et al.
Publicado: (2014)

Lactate clearance as a useful biomarker for the prediction of all-cause mortality in critically ill patients: a systematic review study protocol
por: Zhang, Zhongheng, et al.
Publicado: (2014)

IMPOSE (IMProving Outcomes after Sepsis)—the effect of a multidisciplinary follow-up service on health-related quality of life in patients postsepsis syndromes—a double-blinded randomised controlled trial: protocol
por: Paratz, Jennifer D, et al.
Publicado: (2014)

Effect of supervised aerobic exercise rehabilitation on physical fitness and quality-of-life in survivors of critical illness: an exploratory minimized controlled trial (PIX study)
por: Batterham, A. M., et al.
Publicado: (2014)

Recombinant human activated protein C for the treatment of severe sepsis and septic shock: a study protocol for incorporating observational evidence using a Bayesian approach
por: Zhang, Zhongheng
Publicado: (2014)

Short-term use of remifentanil during endotracheal extubation for prophylactic analgesia in neurosurgical patients after craniotomy (SURE after Craniotomy Study): a study protocol and statistical analysis plan for a randomised controlled trial
por: Wu, Yuan-Xing, et al.
Publicado: (2014)

Cost-effectiveness of a quality improvement programme to reduce central line-associated bloodstream infections in intensive care units in the USA
por: Herzer, Kurt R, et al.
Publicado: (2014)

The Esophageal Pressure-Guided Ventilation 2 (EPVent2) trial protocol: a multicentre, randomised clinical trial of mechanical ventilation guided by transpulmonary pressure
por: Fish, Emily, et al.
Publicado: (2014)

The General Weakness Syndrome Therapy (GymNAST) study: protocol for a cohort study on recovery on walking function
por: Mehrholz, Jan, et al.
Publicado: (2014)

Procalcitonin as a predictor of moderate to severe acute respiratory distress syndrome after cardiac surgery with cardiopulmonary bypass: a study protocol for a prospective cohort study
por: Chen, Han, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_1h1413jei1jj9ing76je66bcb6