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Dihydroorotate dehydrogenase promotes cell proliferation and suppresses cell death in esophageal squamous cell carcinoma and colorectal carcinoma

BACKGROUND: Ferroptosis is defined as an iron-dependent non-apoptotic form of programmed cell death. Dihydroorotate dehydrogenase (DHODH) is a newly discovered anti-ferroptosis molecule independent from the well-known GPX4 and AIFM2. However, the expression pattern and especially the functional role...

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Detalles Bibliográficos
Autores principales: Shi, Zhi-Zhou, Jin, Xin, Li, Wen-Ting, Tao, Hao, Song, Sheng-Jie, Fan, Ze-Wen, Jiang, Wen, Liang, Jian-Wei, Bai, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10583008/
https://www.ncbi.nlm.nih.gov/pubmed/37859742
http://dx.doi.org/10.21037/tcr-23-136