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Microglial P2X4 receptors are essential for spinal neurons hyperexcitability and tactile allodynia in male and female neuropathic mice

In neuropathic pain, recent evidence has highlighted a sex-dependent role of the P2X4 receptor in spinal microglia in the development of tactile allodynia following nerve injury. Here, using internalization-defective P2X4mCherryIN knockin mice (P2X4KI), we demonstrate that increased cell surface exp...

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Detalles Bibliográficos
Autores principales:	Gilabert, Damien, Duveau, Alexia, Carracedo, Sara, Linck, Nathalie, Langla, Adeline, Muramatsu, Rieko, Koch-Nolte, Friedrich, Rassendren, François, Grutter, Thomas, Fossat, Pascal, Boué-Grabot, Eric, Ulmann, Lauriane
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10583052/ https://www.ncbi.nlm.nih.gov/pubmed/37860691 http://dx.doi.org/10.1016/j.isci.2023.108110

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