Polygenic risk score predicts risk of primary sclerosing cholangitis in inflammatory bowel disease

BACKGROUND: Forty distinct primary sclerosing cholangitis (PSC) genomic loci have been identified through multiancestry meta-analyses. The polygenic risk score (PRS) could serve as a promising tool to discover unique disease behaviour, like PSC, underlying inflammatory bowel disease (IBD). AIM: To t...

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Detalles Bibliográficos
Autores principales: Wang, Ming-Hsi, Friton, Jessica J, Raffals, Laura E, Leighton, Jonathan A, Pasha, Shabana F, Picco, Michael F, Monroe, Kelly, Nix, Billy D, Newberry, Rodney D, Faubion, William A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Inflammatory Bowel Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10583098/
https://www.ncbi.nlm.nih.gov/pubmed/37832963
http://dx.doi.org/10.1136/bmjgast-2023-001141

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10583098/
https://www.ncbi.nlm.nih.gov/pubmed/37832963
http://dx.doi.org/10.1136/bmjgast-2023-001141

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