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Percutaneous Left Atrial Appendage Occlusion: What the Practising Physician Should Know

Non-valvular AF is a common clinical condition associated with an increased risk of thromboembolic complications. As a consequence, oral anticoagulant therapy (OAT) is the cornerstone of non-valvular AF management. Despite the well-established efficacy of OAT, many patients cannot receive this preve...

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Autores principales: Merella, Pierluigi, Talanas, Giuseppe, Lorenzoni, Giovanni, Denurra, Cristiana, Atzori, Enrico, Casu, Gavino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Radcliffe Cardiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10583154/
https://www.ncbi.nlm.nih.gov/pubmed/37860701
http://dx.doi.org/10.15420/ecr.2023.18
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author Merella, Pierluigi
Talanas, Giuseppe
Lorenzoni, Giovanni
Denurra, Cristiana
Atzori, Enrico
Casu, Gavino
author_facet Merella, Pierluigi
Talanas, Giuseppe
Lorenzoni, Giovanni
Denurra, Cristiana
Atzori, Enrico
Casu, Gavino
author_sort Merella, Pierluigi
collection PubMed
description Non-valvular AF is a common clinical condition associated with an increased risk of thromboembolic complications. As a consequence, oral anticoagulant therapy (OAT) is the cornerstone of non-valvular AF management. Despite the well-established efficacy of OAT, many patients cannot receive this preventive therapy due to bleeding or a high risk of bleeding. The fact that more than 90% of thrombi are formed in the left atrial appendage has led to the development of alternative methods to reduce the embolic risk. Left atrial appendage occlusion (LAAO) is a non-pharmacological option for preventing cardioembolic events in patients with non-valvular AF with a contraindication to OAT. The demand for LAAO procedures is growing exponentially and clinicians should consider this alternative option when managing patients with a contraindication to OAT. This review summarises the current thinking about LAAO.
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spelling pubmed-105831542023-10-19 Percutaneous Left Atrial Appendage Occlusion: What the Practising Physician Should Know Merella, Pierluigi Talanas, Giuseppe Lorenzoni, Giovanni Denurra, Cristiana Atzori, Enrico Casu, Gavino Eur Cardiol Atrial Fibrillation Non-valvular AF is a common clinical condition associated with an increased risk of thromboembolic complications. As a consequence, oral anticoagulant therapy (OAT) is the cornerstone of non-valvular AF management. Despite the well-established efficacy of OAT, many patients cannot receive this preventive therapy due to bleeding or a high risk of bleeding. The fact that more than 90% of thrombi are formed in the left atrial appendage has led to the development of alternative methods to reduce the embolic risk. Left atrial appendage occlusion (LAAO) is a non-pharmacological option for preventing cardioembolic events in patients with non-valvular AF with a contraindication to OAT. The demand for LAAO procedures is growing exponentially and clinicians should consider this alternative option when managing patients with a contraindication to OAT. This review summarises the current thinking about LAAO. Radcliffe Cardiology 2023-09-28 /pmc/articles/PMC10583154/ /pubmed/37860701 http://dx.doi.org/10.15420/ecr.2023.18 Text en Copyright © The Author(s), 2023. Published by Radcliffe Group Ltd. https://creativecommons.org/licenses/by-nc/4.0/This work is open access under the CC-BY-NC 4.0 License which allows users to copy, redistribute and make derivative works for non-commercial purposes, provided the original work is cited correctly.
spellingShingle Atrial Fibrillation
Merella, Pierluigi
Talanas, Giuseppe
Lorenzoni, Giovanni
Denurra, Cristiana
Atzori, Enrico
Casu, Gavino
Percutaneous Left Atrial Appendage Occlusion: What the Practising Physician Should Know
title Percutaneous Left Atrial Appendage Occlusion: What the Practising Physician Should Know
title_full Percutaneous Left Atrial Appendage Occlusion: What the Practising Physician Should Know
title_fullStr Percutaneous Left Atrial Appendage Occlusion: What the Practising Physician Should Know
title_full_unstemmed Percutaneous Left Atrial Appendage Occlusion: What the Practising Physician Should Know
title_short Percutaneous Left Atrial Appendage Occlusion: What the Practising Physician Should Know
title_sort percutaneous left atrial appendage occlusion: what the practising physician should know
topic Atrial Fibrillation
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10583154/
https://www.ncbi.nlm.nih.gov/pubmed/37860701
http://dx.doi.org/10.15420/ecr.2023.18
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