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Percutaneous Left Atrial Appendage Occlusion: What the Practising Physician Should Know
Non-valvular AF is a common clinical condition associated with an increased risk of thromboembolic complications. As a consequence, oral anticoagulant therapy (OAT) is the cornerstone of non-valvular AF management. Despite the well-established efficacy of OAT, many patients cannot receive this preve...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Radcliffe Cardiology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10583154/ https://www.ncbi.nlm.nih.gov/pubmed/37860701 http://dx.doi.org/10.15420/ecr.2023.18 |
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author | Merella, Pierluigi Talanas, Giuseppe Lorenzoni, Giovanni Denurra, Cristiana Atzori, Enrico Casu, Gavino |
author_facet | Merella, Pierluigi Talanas, Giuseppe Lorenzoni, Giovanni Denurra, Cristiana Atzori, Enrico Casu, Gavino |
author_sort | Merella, Pierluigi |
collection | PubMed |
description | Non-valvular AF is a common clinical condition associated with an increased risk of thromboembolic complications. As a consequence, oral anticoagulant therapy (OAT) is the cornerstone of non-valvular AF management. Despite the well-established efficacy of OAT, many patients cannot receive this preventive therapy due to bleeding or a high risk of bleeding. The fact that more than 90% of thrombi are formed in the left atrial appendage has led to the development of alternative methods to reduce the embolic risk. Left atrial appendage occlusion (LAAO) is a non-pharmacological option for preventing cardioembolic events in patients with non-valvular AF with a contraindication to OAT. The demand for LAAO procedures is growing exponentially and clinicians should consider this alternative option when managing patients with a contraindication to OAT. This review summarises the current thinking about LAAO. |
format | Online Article Text |
id | pubmed-10583154 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Radcliffe Cardiology |
record_format | MEDLINE/PubMed |
spelling | pubmed-105831542023-10-19 Percutaneous Left Atrial Appendage Occlusion: What the Practising Physician Should Know Merella, Pierluigi Talanas, Giuseppe Lorenzoni, Giovanni Denurra, Cristiana Atzori, Enrico Casu, Gavino Eur Cardiol Atrial Fibrillation Non-valvular AF is a common clinical condition associated with an increased risk of thromboembolic complications. As a consequence, oral anticoagulant therapy (OAT) is the cornerstone of non-valvular AF management. Despite the well-established efficacy of OAT, many patients cannot receive this preventive therapy due to bleeding or a high risk of bleeding. The fact that more than 90% of thrombi are formed in the left atrial appendage has led to the development of alternative methods to reduce the embolic risk. Left atrial appendage occlusion (LAAO) is a non-pharmacological option for preventing cardioembolic events in patients with non-valvular AF with a contraindication to OAT. The demand for LAAO procedures is growing exponentially and clinicians should consider this alternative option when managing patients with a contraindication to OAT. This review summarises the current thinking about LAAO. Radcliffe Cardiology 2023-09-28 /pmc/articles/PMC10583154/ /pubmed/37860701 http://dx.doi.org/10.15420/ecr.2023.18 Text en Copyright © The Author(s), 2023. Published by Radcliffe Group Ltd. https://creativecommons.org/licenses/by-nc/4.0/This work is open access under the CC-BY-NC 4.0 License which allows users to copy, redistribute and make derivative works for non-commercial purposes, provided the original work is cited correctly. |
spellingShingle | Atrial Fibrillation Merella, Pierluigi Talanas, Giuseppe Lorenzoni, Giovanni Denurra, Cristiana Atzori, Enrico Casu, Gavino Percutaneous Left Atrial Appendage Occlusion: What the Practising Physician Should Know |
title | Percutaneous Left Atrial Appendage Occlusion: What the Practising Physician Should Know |
title_full | Percutaneous Left Atrial Appendage Occlusion: What the Practising Physician Should Know |
title_fullStr | Percutaneous Left Atrial Appendage Occlusion: What the Practising Physician Should Know |
title_full_unstemmed | Percutaneous Left Atrial Appendage Occlusion: What the Practising Physician Should Know |
title_short | Percutaneous Left Atrial Appendage Occlusion: What the Practising Physician Should Know |
title_sort | percutaneous left atrial appendage occlusion: what the practising physician should know |
topic | Atrial Fibrillation |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10583154/ https://www.ncbi.nlm.nih.gov/pubmed/37860701 http://dx.doi.org/10.15420/ecr.2023.18 |
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