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P-MSC-derived extracellular vesicles facilitate diabetic wound healing via miR-145-5p/ CDKN1A-mediated functional improvements of high glucose-induced senescent fibroblasts

BACKGROUND: Persistent hyperglycaemia in diabetes causes functional abnormalities of human dermal fibroblasts (HDFs), partially leading to delayed skin wound healing. Extracellular vesicles (EVs) containing multiple pro-healing microRNAs (miRNAs) have been shown to exert therapeutic effects on diabe...

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Detalles Bibliográficos
Autores principales:	Su, Jianlong, Wei, Qian, Ma, Kui, Wang, Yaxi, Hu, Wenzhi, Meng, Hao, Li, Qiankun, Zhang, Yuehou, Zhang, Wenhua, Li, Haihong, Fu, Xiaobing, Zhang, Cuiping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10583213/ https://www.ncbi.nlm.nih.gov/pubmed/37860579 http://dx.doi.org/10.1093/burnst/tkad010

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