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Item response theory in early phase clinical trials: Utilization of a reference model to analyze the Montgomery‐Åsberg Depression Rating Scale

In clinical trials, Montgomery‐Åsberg Depression Rating Scale (MADRS) questionnaire data are added up to total scores before analysis, assuming equal contribution of each separate question. Item Response Theory (IRT)‐based analysis avoids this by using individual question responses to determine the...

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Detalles Bibliográficos
Autores principales:	Otto, Marije E., Bergmann, Kirsten R., de Kam, Marieke L., Recourt, Kasper, Jacobs, Gabriël E., van Esdonk, Michiel J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10583236/ https://www.ncbi.nlm.nih.gov/pubmed/37551774 http://dx.doi.org/10.1002/psp4.13018

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