Multivariate modeling of magnetic resonance biomarkers and clinical outcome measures for Duchenne muscular dystrophy clinical trials

Although regulatory agencies encourage inclusion of imaging biomarkers in clinical trials for Duchenne muscular dystrophy (DMD), industry receives minimal guidance on how to use these biomarkers most beneficially in trials. This study aims to identify the optimal use of muscle fat fraction biomarker...

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Detalles Bibliográficos
Autores principales: Kim, Sarah, Willcocks, Rebecca J., Daniels, Michael J., Morales, Juan Francisco, Yoon, Deok Yong, Triplett, William T., Barnard, Alison M., Conrado, Daniela J., Aggarwal, Varun, Belfiore‐Oshan, Ramona, Martinez, Terina N., Walter, Glenn A., Rooney, William D., Vandenborne, Krista
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10583249/
https://www.ncbi.nlm.nih.gov/pubmed/37534782
http://dx.doi.org/10.1002/psp4.13021

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