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Accelerated DNA methylation age plays a role in the impact of cardiovascular risk factors on the human heart

BACKGROUND: DNA methylation (DNAm) age acceleration (AgeAccel) and cardiac age by 12-lead advanced electrocardiography (A-ECG) are promising biomarkers of biological and cardiac aging, respectively. We aimed to explore the relationships between DNAm age and A-ECG heart age and to understand the exte...

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Detalles Bibliográficos
Autores principales: Topriceanu, Constantin-Cristian, Dev, Eesha, Ahmad, Mahmood, Hughes, Rebecca, Shiwani, Hunain, Webber, Matthew, Direk, Kenan, Wong, Andrew, Ugander, Martin, Moon, James C., Hughes, Alun D., Maddock, Jane, Schlegel, Todd T., Captur, Gabriella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10583368/
https://www.ncbi.nlm.nih.gov/pubmed/37853450
http://dx.doi.org/10.1186/s13148-023-01576-9