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Novel polymorphisms in the prion protein gene (PRNP) and stability of the resultant prion protein in different horse breeds

Prion diseases are fatal neurodegenerative disorders in which the main pathogenic event is the conversion of the cellular prion protein (PrP(C)) into an abnormal and misfolded isoform known as PrP(Sc). Most prion diseases and their susceptibility and pathogenesis are mainly modulated by the PRNP gen...

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Detalles Bibliográficos
Autores principales:	Sola, Diego, Artigas, Rody, Mediano, Diego R., Zaragoza, Pilar, Badiola, Juan José, Martín-Burriel, Inmaculada, Acín, Cristina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10583458/ https://www.ncbi.nlm.nih.gov/pubmed/37848924 http://dx.doi.org/10.1186/s13567-023-01211-8

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