Colon Conundrum: A Fascinating Case Report Unraveling the Enigmatic Tactoid Bodies

Tactile corpuscle-like bodies (TCLBs) are specialized mechanoreceptors found in the dermal papilla of glabrous skin. They are normally not found in the gastrointestinal (GI) mucosa. There has been an increase in incidental detection in the GI mucosa due to the widespread use of colonoscopy procedure...

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Detalles Bibliográficos
Autores principales: Gofar, Kebire, Yearsley, Martha, Gallardo, Matthew, Ghebrat, Hermon B, Chakraborty, Subhankar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Gastroenterology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10583482/
https://www.ncbi.nlm.nih.gov/pubmed/37859887
http://dx.doi.org/10.7759/cureus.45444
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author Gofar, Kebire
Yearsley, Martha
Gallardo, Matthew
Ghebrat, Hermon B
Chakraborty, Subhankar
author_facet Gofar, Kebire
Yearsley, Martha
Gallardo, Matthew
Ghebrat, Hermon B
Chakraborty, Subhankar
author_sort Gofar, Kebire
collection PubMed
description Tactile corpuscle-like bodies (TCLBs) are specialized mechanoreceptors found in the dermal papilla of glabrous skin. They are normally not found in the gastrointestinal (GI) mucosa. There has been an increase in incidental detection in the GI mucosa due to the widespread use of colonoscopy procedures. However, TCLB's clinical implications in the GI tract remain unknown. We present a case of a 74-year-old man who was noted to have TCLBs in the rectosigmoid mucosa following resection for iatrogenic perforation. The TCLBs were spindle-shaped, positive for S-100, and negative for CD68. We review the literature on TCLBs in the GI tract and discuss their potential function in the GI mucosa.
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spelling pubmed-105834822023-10-19 Colon Conundrum: A Fascinating Case Report Unraveling the Enigmatic Tactoid Bodies Gofar, Kebire Yearsley, Martha Gallardo, Matthew Ghebrat, Hermon B Chakraborty, Subhankar Cureus Gastroenterology Tactile corpuscle-like bodies (TCLBs) are specialized mechanoreceptors found in the dermal papilla of glabrous skin. They are normally not found in the gastrointestinal (GI) mucosa. There has been an increase in incidental detection in the GI mucosa due to the widespread use of colonoscopy procedures. However, TCLB's clinical implications in the GI tract remain unknown. We present a case of a 74-year-old man who was noted to have TCLBs in the rectosigmoid mucosa following resection for iatrogenic perforation. The TCLBs were spindle-shaped, positive for S-100, and negative for CD68. We review the literature on TCLBs in the GI tract and discuss their potential function in the GI mucosa. Cureus 2023-09-18 /pmc/articles/PMC10583482/ /pubmed/37859887 http://dx.doi.org/10.7759/cureus.45444 Text en Copyright © 2023, Gofar et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Gastroenterology
Gofar, Kebire
Yearsley, Martha
Gallardo, Matthew
Ghebrat, Hermon B
Chakraborty, Subhankar
Colon Conundrum: A Fascinating Case Report Unraveling the Enigmatic Tactoid Bodies
title Colon Conundrum: A Fascinating Case Report Unraveling the Enigmatic Tactoid Bodies
title_full Colon Conundrum: A Fascinating Case Report Unraveling the Enigmatic Tactoid Bodies
title_fullStr Colon Conundrum: A Fascinating Case Report Unraveling the Enigmatic Tactoid Bodies
title_full_unstemmed Colon Conundrum: A Fascinating Case Report Unraveling the Enigmatic Tactoid Bodies
title_short Colon Conundrum: A Fascinating Case Report Unraveling the Enigmatic Tactoid Bodies
title_sort colon conundrum: a fascinating case report unraveling the enigmatic tactoid bodies
topic Gastroenterology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10583482/
https://www.ncbi.nlm.nih.gov/pubmed/37859887
http://dx.doi.org/10.7759/cureus.45444
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