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Comparison of Body Composition Variables between Post-Bariatric Surgery Patients and Non-Operative Controls

BACKGROUND: Since bariatric surgery results in massive weight loss, it may be associated with a disproportionate decrease in lean body mass. OBJECTIVE: To evaluate body composition in post-bariatric surgery patients who had a successful weight loss at 12 months (>50% excess weight loss) with comp...

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Autores principales: Tangjittrong, Sirinrat, Udomsawaengsup, Suthep, Boonchaya-anant, Patchaya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10583510/
https://www.ncbi.nlm.nih.gov/pubmed/37860720
http://dx.doi.org/10.1177/11795514231206731
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author Tangjittrong, Sirinrat
Udomsawaengsup, Suthep
Boonchaya-anant, Patchaya
author_facet Tangjittrong, Sirinrat
Udomsawaengsup, Suthep
Boonchaya-anant, Patchaya
author_sort Tangjittrong, Sirinrat
collection PubMed
description BACKGROUND: Since bariatric surgery results in massive weight loss, it may be associated with a disproportionate decrease in lean body mass. OBJECTIVE: To evaluate body composition in post-bariatric surgery patients who had a successful weight loss at 12 months (>50% excess weight loss) with comparisons to healthy controls who were matched for age, sex and BMI. METHODS: This is an observational analytic study using data from post-bariatric surgery patients who had laparoscopic Roux-en-Y gastric bypass (RYGB) or laparoscopic sleeve gastrectomy (SG) at King Chulalongkorn Memorial Hospital. Patients who had percentage excessive weight loss (%EWL) >50% and achieved a BMI of <30 kg/m(2) within 12 months after the surgery were included. Non-operative healthy controls matched for sex, age, and BMI (1:1) were recruited. The 12-month post-bariatric surgery BMI was used to match the BMI of the control subjects. A single bioelectrical impedance analysis (BIA) (Inbody 770) machine was used for the entire study. RESULTS: Sixty participants were included in this study. There are 30 post-bariatric surgery patients (female n = 19, male n = 11) and 30 non-operative controls (female n = 19, male n = 11). The 12-month post-bariatric surgery patients had lower percentage of body fat (PBF) (30.6% vs 35.9%, P-value .001) and trunk fat mass (10.3 vs 12.4 kg, P-value .04) than non-operative controls. The 12-month post-bariatric surgery patients also were found to have more soft lean mass (SLM) (47.7 vs 39.9 kg, P-value .001), fat free mass (FFM) (51.1 vs 42.3 kg, P-value .001), skeletal muscle mass (SMM) (27.5 vs 23 kg, P-value .003), and trunk lean mass (21.2 vs 19 kg, P-value .02). CONCLUSION: Despite the significant reductions in all body composition variables in post-bariatric surgery patients at 12-month follow-up, both fat free mass and skeletal muscle mass were found to be higher in the surgical patients compared to the control group. CLINICAL TRIALS: Thai Clinical Trials Registry, https://thaiclinicaltrials.org/ ID:TCTR20200223003
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spelling pubmed-105835102023-10-19 Comparison of Body Composition Variables between Post-Bariatric Surgery Patients and Non-Operative Controls Tangjittrong, Sirinrat Udomsawaengsup, Suthep Boonchaya-anant, Patchaya Clin Med Insights Endocrinol Diabetes Original Research BACKGROUND: Since bariatric surgery results in massive weight loss, it may be associated with a disproportionate decrease in lean body mass. OBJECTIVE: To evaluate body composition in post-bariatric surgery patients who had a successful weight loss at 12 months (>50% excess weight loss) with comparisons to healthy controls who were matched for age, sex and BMI. METHODS: This is an observational analytic study using data from post-bariatric surgery patients who had laparoscopic Roux-en-Y gastric bypass (RYGB) or laparoscopic sleeve gastrectomy (SG) at King Chulalongkorn Memorial Hospital. Patients who had percentage excessive weight loss (%EWL) >50% and achieved a BMI of <30 kg/m(2) within 12 months after the surgery were included. Non-operative healthy controls matched for sex, age, and BMI (1:1) were recruited. The 12-month post-bariatric surgery BMI was used to match the BMI of the control subjects. A single bioelectrical impedance analysis (BIA) (Inbody 770) machine was used for the entire study. RESULTS: Sixty participants were included in this study. There are 30 post-bariatric surgery patients (female n = 19, male n = 11) and 30 non-operative controls (female n = 19, male n = 11). The 12-month post-bariatric surgery patients had lower percentage of body fat (PBF) (30.6% vs 35.9%, P-value .001) and trunk fat mass (10.3 vs 12.4 kg, P-value .04) than non-operative controls. The 12-month post-bariatric surgery patients also were found to have more soft lean mass (SLM) (47.7 vs 39.9 kg, P-value .001), fat free mass (FFM) (51.1 vs 42.3 kg, P-value .001), skeletal muscle mass (SMM) (27.5 vs 23 kg, P-value .003), and trunk lean mass (21.2 vs 19 kg, P-value .02). CONCLUSION: Despite the significant reductions in all body composition variables in post-bariatric surgery patients at 12-month follow-up, both fat free mass and skeletal muscle mass were found to be higher in the surgical patients compared to the control group. CLINICAL TRIALS: Thai Clinical Trials Registry, https://thaiclinicaltrials.org/ ID:TCTR20200223003 SAGE Publications 2023-10-17 /pmc/articles/PMC10583510/ /pubmed/37860720 http://dx.doi.org/10.1177/11795514231206731 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Original Research
Tangjittrong, Sirinrat
Udomsawaengsup, Suthep
Boonchaya-anant, Patchaya
Comparison of Body Composition Variables between Post-Bariatric Surgery Patients and Non-Operative Controls
title Comparison of Body Composition Variables between Post-Bariatric Surgery Patients and Non-Operative Controls
title_full Comparison of Body Composition Variables between Post-Bariatric Surgery Patients and Non-Operative Controls
title_fullStr Comparison of Body Composition Variables between Post-Bariatric Surgery Patients and Non-Operative Controls
title_full_unstemmed Comparison of Body Composition Variables between Post-Bariatric Surgery Patients and Non-Operative Controls
title_short Comparison of Body Composition Variables between Post-Bariatric Surgery Patients and Non-Operative Controls
title_sort comparison of body composition variables between post-bariatric surgery patients and non-operative controls
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10583510/
https://www.ncbi.nlm.nih.gov/pubmed/37860720
http://dx.doi.org/10.1177/11795514231206731
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