Cargando…

Lifestyle Factors Associated With Erosive Esophagitis in Japanese Individuals With and Without Obesity Undergoing Health Checkups

BACKGROUND: Several lifestyle factors have been reported to be associated with erosive esophagitis (EE). Many studies examined the associated factors for EE independent of obesity. However, lifestyle factors associated with EE might differ depending on sex or the presence of obesity. This study thus...

Descripción completa

Detalles Bibliográficos
Autores principales: Shiota, Seiji, Shibata, Aika, Horinouchi, Noboru, Yamamoto, Kyoko, Miyazaki, Eishi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10583521/
https://www.ncbi.nlm.nih.gov/pubmed/37846060
http://dx.doi.org/10.1177/21501319231205383
_version_ 1785122572156796928
author Shiota, Seiji
Shibata, Aika
Horinouchi, Noboru
Yamamoto, Kyoko
Miyazaki, Eishi
author_facet Shiota, Seiji
Shibata, Aika
Horinouchi, Noboru
Yamamoto, Kyoko
Miyazaki, Eishi
author_sort Shiota, Seiji
collection PubMed
description BACKGROUND: Several lifestyle factors have been reported to be associated with erosive esophagitis (EE). Many studies examined the associated factors for EE independent of obesity. However, lifestyle factors associated with EE might differ depending on sex or the presence of obesity. This study thus aimed to investigate the lifestyle risk factors for EE stratified by obesity and sex. METHODS: A cross-sectional survey was conducted among Japanese people who underwent an annual health checkup at the Oita Health Checkup Center between 2019 and 2021. Multivariate analysis was performed to determine the factors associated with EE in participants stratified by sex and the presence of obesity. RESULTS: EE was diagnosed in 676 of 5240 participants (12.9%) who were analyzed, and occurred most often in males (601 cases). The percentage of obesity based on body mass index was significantly higher among EE than non-EE participants (50.3% and 26.5%, P < .001). In obese males, eating just before bedtime (OR = 1.34, 95% CI 1.01-1.78) and hiatal hernia (OR = 3.42, 95% CI 2.57-4.54) were significantly associated with EE in multivariate analysis. In non-obese males, current smoking (OR = 1.48, 95% CI 1.07-2.04), alcohol consumption of 40 to 60 g/day (OR = 1.60, 95% CI 1.11-2.30), and hiatal hernia (OR = 3.63, 95% CI 2.79-4.73) were significantly associated with EE. CONCLUSIONS: We found that factors associated with EE were different between obese and non-obese males. In obese males, avoiding going to bed within 2 h after dinner might contribute to preventing the occurrence of EE. In non-obese males, prevention of obesity, quitting smoking, and avoiding heavy alcohol consumption might be important for preventing the development of EE.
format Online
Article
Text
id pubmed-10583521
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher SAGE Publications
record_format MEDLINE/PubMed
spelling pubmed-105835212023-10-19 Lifestyle Factors Associated With Erosive Esophagitis in Japanese Individuals With and Without Obesity Undergoing Health Checkups Shiota, Seiji Shibata, Aika Horinouchi, Noboru Yamamoto, Kyoko Miyazaki, Eishi J Prim Care Community Health Original Research BACKGROUND: Several lifestyle factors have been reported to be associated with erosive esophagitis (EE). Many studies examined the associated factors for EE independent of obesity. However, lifestyle factors associated with EE might differ depending on sex or the presence of obesity. This study thus aimed to investigate the lifestyle risk factors for EE stratified by obesity and sex. METHODS: A cross-sectional survey was conducted among Japanese people who underwent an annual health checkup at the Oita Health Checkup Center between 2019 and 2021. Multivariate analysis was performed to determine the factors associated with EE in participants stratified by sex and the presence of obesity. RESULTS: EE was diagnosed in 676 of 5240 participants (12.9%) who were analyzed, and occurred most often in males (601 cases). The percentage of obesity based on body mass index was significantly higher among EE than non-EE participants (50.3% and 26.5%, P < .001). In obese males, eating just before bedtime (OR = 1.34, 95% CI 1.01-1.78) and hiatal hernia (OR = 3.42, 95% CI 2.57-4.54) were significantly associated with EE in multivariate analysis. In non-obese males, current smoking (OR = 1.48, 95% CI 1.07-2.04), alcohol consumption of 40 to 60 g/day (OR = 1.60, 95% CI 1.11-2.30), and hiatal hernia (OR = 3.63, 95% CI 2.79-4.73) were significantly associated with EE. CONCLUSIONS: We found that factors associated with EE were different between obese and non-obese males. In obese males, avoiding going to bed within 2 h after dinner might contribute to preventing the occurrence of EE. In non-obese males, prevention of obesity, quitting smoking, and avoiding heavy alcohol consumption might be important for preventing the development of EE. SAGE Publications 2023-10-16 /pmc/articles/PMC10583521/ /pubmed/37846060 http://dx.doi.org/10.1177/21501319231205383 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Original Research
Shiota, Seiji
Shibata, Aika
Horinouchi, Noboru
Yamamoto, Kyoko
Miyazaki, Eishi
Lifestyle Factors Associated With Erosive Esophagitis in Japanese Individuals With and Without Obesity Undergoing Health Checkups
title Lifestyle Factors Associated With Erosive Esophagitis in Japanese Individuals With and Without Obesity Undergoing Health Checkups
title_full Lifestyle Factors Associated With Erosive Esophagitis in Japanese Individuals With and Without Obesity Undergoing Health Checkups
title_fullStr Lifestyle Factors Associated With Erosive Esophagitis in Japanese Individuals With and Without Obesity Undergoing Health Checkups
title_full_unstemmed Lifestyle Factors Associated With Erosive Esophagitis in Japanese Individuals With and Without Obesity Undergoing Health Checkups
title_short Lifestyle Factors Associated With Erosive Esophagitis in Japanese Individuals With and Without Obesity Undergoing Health Checkups
title_sort lifestyle factors associated with erosive esophagitis in japanese individuals with and without obesity undergoing health checkups
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10583521/
https://www.ncbi.nlm.nih.gov/pubmed/37846060
http://dx.doi.org/10.1177/21501319231205383
work_keys_str_mv AT shiotaseiji lifestylefactorsassociatedwitherosiveesophagitisinjapaneseindividualswithandwithoutobesityundergoinghealthcheckups
AT shibataaika lifestylefactorsassociatedwitherosiveesophagitisinjapaneseindividualswithandwithoutobesityundergoinghealthcheckups
AT horinouchinoboru lifestylefactorsassociatedwitherosiveesophagitisinjapaneseindividualswithandwithoutobesityundergoinghealthcheckups
AT yamamotokyoko lifestylefactorsassociatedwitherosiveesophagitisinjapaneseindividualswithandwithoutobesityundergoinghealthcheckups
AT miyazakieishi lifestylefactorsassociatedwitherosiveesophagitisinjapaneseindividualswithandwithoutobesityundergoinghealthcheckups