Cargando…

Deciphering Evolutionary Trajectories of Lactate Dehydrogenases Provides New Insights into Allostery

Lactate dehydrogenase (LDH, EC.1.1.127) is an important enzyme engaged in the anaerobic metabolism of cells, catalyzing the conversion of pyruvate to lactate and NADH to NAD(+). LDH is a relevant enzyme to investigate structure–function relationships. The present work provides the missing link in ou...

Descripción completa

Detalles Bibliográficos
Autores principales:	Robin, Adeline Y, Brochier-Armanet, Céline, Bertrand, Quentin, Barette, Caroline, Girard, Eric, Madern, Dominique
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Discoveries
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10583557/ https://www.ncbi.nlm.nih.gov/pubmed/37797308 http://dx.doi.org/10.1093/molbev/msad223

Ejemplares similares

Protein Conformational Space at the Edge of Allostery: Turning a Nonallosteric Malate Dehydrogenase into an “Allosterized” Enzyme Using Evolution-Guided Punctual Mutations
por: Iorio, Antonio, et al.
Publicado: (2022)

Resurrection of Ancestral Malate Dehydrogenases Reveals the Evolutionary History of Halobacterial Proteins: Deciphering Gene Trajectories and Changes in Biochemical Properties
por: Blanquart, Samuel, et al.
Publicado: (2021)

Phylogenomic Test of the Hypotheses for the Evolutionary Origin of Eukaryotes
por: Rochette, Nicolas C., et al.
Publicado: (2014)

A Comprehensive Evolutionary Scenario of Cell Division and Associated Processes in the Firmicutes
por: Garcia, Pierre S, et al.
Publicado: (2021)

The Molecular Determinants of Thermoadaptation: Methanococcales as a Case Study
por: Lecocq, Michel, et al.
Publicado: (2020)

A DNA topoisomerase IB in Thaumarchaeota testifies for the presence of this enzyme in the last common ancestor of Archaea and Eucarya
por: Brochier-Armanet, Céline, et al.
Publicado: (2008)

Evolutionary Trajectories are Contingent on Mitonuclear Interactions
por: Biot-Pelletier, Damien, et al.
Publicado: (2023)

Phylogenomics Uncovers Evolutionary Trajectory of Nitrogen Fixation in Cyanobacteria
por: Chen, Meng-Yun, et al.
Publicado: (2022)

Principles of Cold Adaptation of Fish Lactate Dehydrogenases Revealed by Computer Simulations of the Catalytic Reaction
por: Koenekoop, Lucien, et al.
Publicado: (2023)

Evolutionary Trajectories of New Duplicated and Putative De Novo Genes
por: Montañés, José Carlos, et al.
Publicado: (2023)

Ligand-Binding-Site Structure Shapes Allosteric Signal Transduction and the Evolution of Allostery in Protein Complexes
por: Abrusán, György, et al.
Publicado: (2019)

Distinct Evolutionary Trajectories of Neuronal and Hair Cell Nicotinic Acetylcholine Receptors
por: Marcovich, Irina, et al.
Publicado: (2020)

Functional Constraints on Insect Immune System Components Govern Their Evolutionary Trajectories
por: Ruzzante, Livio, et al.
Publicado: (2021)

Population Bottlenecks Strongly Influence the Evolutionary Trajectory to Fluoroquinolone Resistance in Escherichia coli
por: Garoff, Linnéa, et al.
Publicado: (2020)

Giant viruses, giant chimeras: The multiple evolutionary histories of Mimivirus genes
por: Moreira, David, et al.
Publicado: (2008)

Deciphering the Genetic Basis of Silkworm Cocoon Colors Provides New Insights into Biological Coloration and Phenotypic Diversification
por: Lu, Yaru, et al.
Publicado: (2023)

Pseudogenes Provide Evolutionary Evidence for the Competitive Endogenous RNA Hypothesis
por: Glenfield, Cian, et al.
Publicado: (2018)

Deciphering the Routes of invasion of Drosophila suzukii by Means of ABC Random Forest
por: Fraimout, Antoine, et al.
Publicado: (2017)

Evolutionary history of phosphatidylinositol- 3-kinases: ancestral origin in eukaryotes and complex duplication patterns
por: Philippon, Héloïse, et al.
Publicado: (2015)

Deciphering the Wisent Demographic and Adaptive Histories from Individual Whole-Genome Sequences
por: Gautier, Mathieu, et al.
Publicado: (2016)

The Genome of the Endangered Dryas Monkey Provides New Insights into the Evolutionary History of the Vervets
por: van der Valk, Tom, et al.
Publicado: (2020)

GC-Biased Gene Conversion in Yeast Is Specifically Associated with Crossovers: Molecular Mechanisms and Evolutionary Significance
por: Lesecque, Yann, et al.
Publicado: (2013)

Global Phylogenomic Analysis Disentangles the Complex Evolutionary History of DNA Replication in Archaea
por: Raymann, Kasie, et al.
Publicado: (2014)

Whole-Genome Sequencing of Tibetan Macaque (Macaca thibetana) Provides New Insight into the Macaque Evolutionary History
por: Fan, Zhenxin, et al.
Publicado: (2014)

Comparative Population Transcriptomics Provide New Insight into the Evolutionary History and Adaptive Potential of World Ocean Krill
por: Choquet, Marvin, et al.
Publicado: (2023)

The Evolutionary History of Wild, Domesticated, and Feral Brassica oleracea (Brassicaceae)
por: Mabry, Makenzie E, et al.
Publicado: (2021)

Evolutionary Genomics of a Subdivided Species
por: Maruki, Takahiro, et al.
Publicado: (2022)

Shared Evolutionary Path in Social Microbiomes
por: Frazão, Nelson, et al.
Publicado: (2023)

Divergence in Enzymatic Activities in the Soybean GST Supergene Family Provides New Insight into the Evolutionary Dynamics of Whole-Genome Duplicates
por: Liu, Hai-Jing, et al.
Publicado: (2015)

Complex Evolutionary History With Extensive Ancestral Gene Flow in an African Primate Radiation
por: Jensen, Axel, et al.
Publicado: (2023)

Interface Matters: The Stiffness Route to Stability of a Thermophilic Tetrameric Malate Dehydrogenase
por: Kalimeri, Maria, et al.
Publicado: (2014)

Multiple Genetic Trajectories to Extreme Abiotic Stress Adaptation in Arctic Brassicaceae
por: Birkeland, Siri, et al.
Publicado: (2020)

Evolutionary Dynamics of Abundant Stop Codon Readthrough
por: Jungreis, Irwin, et al.
Publicado: (2016)

Gene Loss Predictably Drives Evolutionary Adaptation
por: Helsen, Jana, et al.
Publicado: (2020)

Molecular Evolutionary Dynamics of Energy Limited Microorganisms
por: Shoemaker, William R, et al.
Publicado: (2021)

Ecological Specialization and Evolutionary Reticulation in Extant Hyaenidae
por: Westbury, Michael V, et al.
Publicado: (2021)

The Genomic Basis of Evolutionary Novelties in a Leafhopper
por: Li, Zheng, et al.
Publicado: (2022)

Evolutionary History of Sexual Differentiation Mechanism in Insects
por: Chikami, Yasuhiko, et al.
Publicado: (2022)

Horizontal gene transfer of a chloroplast DnaJ-Fer protein to Thaumarchaeota and the evolutionary history of the DnaK chaperone system in Archaea
por: Petitjean, Céline, et al.
Publicado: (2012)

Evolutionary Insights into Premetazoan Functions of the Neuronal Protein Homer
por: Burkhardt, Pawel, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_8oe04uf0csnoa6dqs8a0cbcnr2