Synergistic Cytotoxicity of a Toxin Targeting the Epidermal Growth Factor Receptor and the Glycosylated Triterpenoid SO1861 in Prostate Cancer

Treatment of advanced prostate cancer lacks specificity and curative intent. Therefore, the need for new targeted therapeutic approaches is high. In the present study, we generated the new targeted toxin EGF-PE24mutΔREDLK binding to the epidermal growth factor receptor (EGFR) on the surface of prost...

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Detalles Bibliográficos
Autores principales: Fischer, Alexandra, Masilamani, Anie Priscilla, Schultze-Seemann, Susanne, Wolf, Isis, Gratzke, Christian, Fuchs, Hendrik, Wolf, Philipp
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10583583/
https://www.ncbi.nlm.nih.gov/pubmed/37859824
http://dx.doi.org/10.7150/jca.85691

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