Cargando…

Mifepristone inhibits hepatoma growth by enhancing the GR-HSP60-survivin interaction to facilitate survivin degradation

Silencing of heat shock protein 60 (HSP60) suppresses the growth of hepatocellular carcinoma (HCC). Mifepristone inhibits HSP60 mRNA expression in Chlamydophila-infected epithelial cells. The aim of this study was to determine whether mifepristone could inhibit the growth of HCC cells by affecting t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huang, Ya-Hui, Lin, Kwang-Huei, Lai, Ming-Wei, Yeh, Chau-Ting
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2023
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10583585/ https://www.ncbi.nlm.nih.gov/pubmed/37859823 http://dx.doi.org/10.7150/jca.86611

Ejemplares similares

Functional Compartmentalization of HSP60-Survivin Interaction between Mitochondria and Cytosol in Cancer Cells
por: Huang, Ya-Hui, et al.
Publicado: (2019)

Arsenic trioxide targets Hsp60, triggering degradation of p53 and survivin
por: Hu, Xuqiao, et al.
Publicado: (2021)

CCAR2/DBC1 and Hsp60 Positively Regulate Expression of Survivin in Neuroblastoma Cells
por: Kim, Wootae, et al.
Publicado: (2019)

Exosomal survivin facilitates vesicle internalization
por: Gonda, Amber, et al.
Publicado: (2018)

High expression of HSP60 and survivin predicts poor prognosis for oral squamous cell carcinoma patients
por: Zhou, Ying, et al.
Publicado: (2023)

Expression of survivin and its splice variants survivin-2B and survivin-ΔEx3 in breast cancer
por: Ryan, B, et al.
Publicado: (2005)

Ubiquitin-proteasomal degradation of antiapoptotic survivin facilitates induction of apoptosis in prostate cancer cells by pristimerin
por: LIU, YONG BO, et al.
Publicado: (2014)

Survivin-specific CD4+ T cells are decreased in patients with survivin-positive myeloma
por: Locke, Frederick L, et al.
Publicado: (2015)

Survivin, Survivin-2B, and Survivin-deItaEx3 expression in medulloblastoma: biologic markers of tumour morphology and clinical outcome
por: Fangusaro, J R, et al.
Publicado: (2005)

Butein promotes ubiquitination-mediated survivin degradation inhibits tumor growth and overcomes chemoresistance
por: Dong, Xin, et al.
Publicado: (2022)

Deconstructing Survivin: comprehensive genetic analysis of Survivin function by conditional knockout in a vertebrate cell line
por: Yue, Zuojun, et al.
Publicado: (2008)

Survivin 2α: a novel Survivin splice variant expressed in human malignancies
por: Caldas, Hugo, et al.
Publicado: (2005)

Survivin and caspases serum protein levels and survivin variants mRNA expression in sepsis
por: Miliaraki, Marianna, et al.
Publicado: (2021)

Survivin the battle against immunosuppression
por: Manuel, Edwin R., et al.
Publicado: (2012)

The twisted survivin connection to angiogenesis
por: Sanhueza, C., et al.
Publicado: (2015)

Craniopharyngioma: Survivin expression and ultrastructure
por: ZHU, JIANG, et al.
Publicado: (2015)

The Functional Repertoire of Survivin's Tails
por: Wheatley, Sally P
Publicado: (2015)

Serum Survivin Increases in Prolactinoma
por: Dellal, Fatma Dilek, et al.
Publicado: (2015)

Antisense of survivin inhibits cervical cancer growth in mice
por: Xu, Hui, et al.
Publicado: (2019)

Circulating CD9+/GFAP+/survivin+ exosomes in malignant glioma patients following survivin vaccination
por: Galbo, Phillip M., et al.
Publicado: (2017)

Correlation between the levels of survivin and survivin promoter-driven gene expression in cancer and non-cancer cells
por: Konopka, Krystyna, et al.
Publicado: (2008)

The role of survivin in the progression of pancreatic ductal adenocarcinoma (PDAC) and a novel survivin-targeted therapeutic for PDAC
por: Brown, Matthew, et al.
Publicado: (2020)

Efficient inhibition of ovarian cancer by degradable nanoparticle-delivered survivin T34A gene
por: Luo, Li, et al.
Publicado: (2016)

Effect of survivin downregulation by simvastatin on the growth and invasion of salivary adenoid cystic carcinoma
por: Cai, Wen-Yan, et al.
Publicado: (2018)

Author Correction: Butein promotes ubiquitination-mediated survivin degradation inhibits tumor growth and overcomes chemoresistance
por: Dong, Xin, et al.
Publicado: (2023)

Prognostic importance of survivin in breast cancer
por: Kennedy, S M, et al.
Publicado: (2003)

Function of Survivin in Trophoblastic Cells of the Placenta
por: Muschol-Steinmetz, Cornelia, et al.
Publicado: (2013)

Survivin: A molecular biomarker in cancer
por: Jaiswal, Praveen Kumar, et al.
Publicado: (2015)

Survivin and gliomas: A literature review
por: Varughese, Rosilin Kotakkathu, et al.
Publicado: (2016)

Prognostic role of survivin in patients with glioma
por: Zhang, Sunfu, et al.
Publicado: (2018)

Exploring the role of survivin in neuroendocrine neoplasms
por: Hanif, Ahmad, et al.
Publicado: (2020)

Targeting survivin using a combination of miR-494 and survivin shRNA has synergistic effects on the suppression of prostate cancer growth
por: ZHU, JIN, et al.
Publicado: (2016)

Delivery of a survivin promoter-driven antisense survivin-expressing plasmid DNA as a cancer therapeutic: a proof-of-concept study
por: Lin, Kun-Yuan, et al.
Publicado: (2016)

The Survivin −31 Snp in Human Colorectal Cancer Correlates with Survivin Splice Variant Expression and Improved Overall Survival
por: Antonacopoulou, Anna G., et al.
Publicado: (2010)

Nicotinamide phosphorybosiltransferase overexpression in thyroid malignancies and its correlation with tumor stage and with survivin/survivin DEx3 expression
por: Sawicka-Gutaj, Nadia, et al.
Publicado: (2015)

A new survivin tracer tracks, delocalizes and captures endogenous survivin at different subcellular locations and in distinct organelles
por: Beghein, Els, et al.
Publicado: (2016)

Nimesulide inhibited the growth of hypopharyngeal carcinoma cells via suppressing Survivin expression
por: Jia-Jun, Tian, et al.
Publicado: (2012)

Expression of different survivin variants in gastric carcinomas: first clues to a role of survivin-2B in tumour progression
por: Krieg, A, et al.
Publicado: (2002)

Depletion of PAK1 enhances Ubiquitin-mediated Survivin degradation in pancreatic β-cells
por: Chen, Yi-Chun, et al.
Publicado: (2013)

Thyroid hormone inhibits growth of hepatoma cells through induction of miR-214
por: Huang, Po-Shuan, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_jbe4l8tj1oh5pj8p0ame6nf9ci