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Comparison of Pharmacological Therapies in Relapse Rates in Patients With Relapsing-Remitting Multiple Sclerosis

Multiple sclerosis (MS) is a chronic autoimmune neurological disorder that significantly impacts the central nervous system (CNS), which includes the brain and spinal cord. Approximately 2.8 million individuals are believed to be living with MS worldwide. The management of MS has evolved considerabl...

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Autores principales: Etta, Indu, Elballushi, Ruaa, Kolesnyk, Viktoriia, Sia, Kim P, Rehman, Sana, Arif, Sehrish, Moonnumackel, Sania J, Nair, Arun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10583624/
https://www.ncbi.nlm.nih.gov/pubmed/37859931
http://dx.doi.org/10.7759/cureus.45454
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author Etta, Indu
Elballushi, Ruaa
Kolesnyk, Viktoriia
Sia, Kim P
Rehman, Sana
Arif, Sehrish
Moonnumackel, Sania J
Nair, Arun
author_facet Etta, Indu
Elballushi, Ruaa
Kolesnyk, Viktoriia
Sia, Kim P
Rehman, Sana
Arif, Sehrish
Moonnumackel, Sania J
Nair, Arun
author_sort Etta, Indu
collection PubMed
description Multiple sclerosis (MS) is a chronic autoimmune neurological disorder that significantly impacts the central nervous system (CNS), which includes the brain and spinal cord. Approximately 2.8 million individuals are believed to be living with MS worldwide. The management of MS has evolved considerably over the years, offering a multitude of guidelines, diverse treatment options, and different approaches to signs and symptoms. The present systematic literature review serves as a comprehensive analysis of the current therapeutic options for MS. It provides a thorough literature review of Food and Drug Administration (FDA)-approved drugs comparing their various clinical end points while concurrently assessing their risk-benefit ratio. It also provides an extensive review of current guidelines and offers an in-depth examination of the different approaches to MS. Through this multifaceted approach, this paper facilitates easy access to available treatment options and aims to aid healthcare providers in decision-making as well as providing a foundation for future research aimed at enhancing treatment options for MS.
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spelling pubmed-105836242023-10-19 Comparison of Pharmacological Therapies in Relapse Rates in Patients With Relapsing-Remitting Multiple Sclerosis Etta, Indu Elballushi, Ruaa Kolesnyk, Viktoriia Sia, Kim P Rehman, Sana Arif, Sehrish Moonnumackel, Sania J Nair, Arun Cureus Other Multiple sclerosis (MS) is a chronic autoimmune neurological disorder that significantly impacts the central nervous system (CNS), which includes the brain and spinal cord. Approximately 2.8 million individuals are believed to be living with MS worldwide. The management of MS has evolved considerably over the years, offering a multitude of guidelines, diverse treatment options, and different approaches to signs and symptoms. The present systematic literature review serves as a comprehensive analysis of the current therapeutic options for MS. It provides a thorough literature review of Food and Drug Administration (FDA)-approved drugs comparing their various clinical end points while concurrently assessing their risk-benefit ratio. It also provides an extensive review of current guidelines and offers an in-depth examination of the different approaches to MS. Through this multifaceted approach, this paper facilitates easy access to available treatment options and aims to aid healthcare providers in decision-making as well as providing a foundation for future research aimed at enhancing treatment options for MS. Cureus 2023-09-18 /pmc/articles/PMC10583624/ /pubmed/37859931 http://dx.doi.org/10.7759/cureus.45454 Text en Copyright © 2023, Etta et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Other
Etta, Indu
Elballushi, Ruaa
Kolesnyk, Viktoriia
Sia, Kim P
Rehman, Sana
Arif, Sehrish
Moonnumackel, Sania J
Nair, Arun
Comparison of Pharmacological Therapies in Relapse Rates in Patients With Relapsing-Remitting Multiple Sclerosis
title Comparison of Pharmacological Therapies in Relapse Rates in Patients With Relapsing-Remitting Multiple Sclerosis
title_full Comparison of Pharmacological Therapies in Relapse Rates in Patients With Relapsing-Remitting Multiple Sclerosis
title_fullStr Comparison of Pharmacological Therapies in Relapse Rates in Patients With Relapsing-Remitting Multiple Sclerosis
title_full_unstemmed Comparison of Pharmacological Therapies in Relapse Rates in Patients With Relapsing-Remitting Multiple Sclerosis
title_short Comparison of Pharmacological Therapies in Relapse Rates in Patients With Relapsing-Remitting Multiple Sclerosis
title_sort comparison of pharmacological therapies in relapse rates in patients with relapsing-remitting multiple sclerosis
topic Other
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10583624/
https://www.ncbi.nlm.nih.gov/pubmed/37859931
http://dx.doi.org/10.7759/cureus.45454
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