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Drug interaction potential of high-dose rifampicin in patients with pulmonary tuberculosis

Accumulating evidence supports the use of higher doses of rifampicin for tuberculosis (TB) treatment. Rifampicin is a potent inducer of metabolic enzymes and drug transporters, resulting in clinically relevant drug interactions. To assess the drug interaction potential of higher doses of rifampicin,...

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Detalles Bibliográficos
Autores principales: Stemkens, Ralf, de Jager, Veronique, Dawson, Rodney, Diacon, Andreas H., Narunsky, Kim, Padayachee, Sherman D., Boeree, Martin J., van Beek, Stijn W., Colbers, Angela, Coenen, Marieke J. H., Svensson, Elin M., Fuhr, Uwe, Phillips, Patrick P. J., te Brake, Lindsey H. M., Aarnoutse, Rob E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10583668/
https://www.ncbi.nlm.nih.gov/pubmed/37768317
http://dx.doi.org/10.1128/aac.00683-23