A heterologous expression platform in Aspergillus nidulans for the elucidation of cryptic secondary metabolism biosynthetic gene clusters: discovery of the Aspergillus fumigatus sartorypyrone biosynthetic pathway

Aspergillus fumigatus is a serious human pathogen causing life-threatening Aspergillosis in immunocompromised patients. Secondary metabolites (SMs) play an important role in pathogenesis, but the products of many SM biosynthetic gene clusters (BGCs) remain unknown. In this study, we have developed a...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, Shu-Yi, Oakley, C. Elizabeth, Jenkinson, Cory B., Chiang, Yi-Ming, Lee, Ching-Kuo, Jones, Christopher G., Seidler, Paul M., Nelson, Hosea M., Todd, Richard B., Wang, Clay C. C., Oakley, Berl R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10583710/
https://www.ncbi.nlm.nih.gov/pubmed/37860661
http://dx.doi.org/10.1039/d3sc02226a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10583710/
https://www.ncbi.nlm.nih.gov/pubmed/37860661
http://dx.doi.org/10.1039/d3sc02226a

Ejemplares similares