Screening and optimization of phage display cyclic peptides against the WDR5 WBM site

Of the various WD40 family proteins, WDR5 is a particularly important multifunctional adaptor protein that can bind to several protein complexes to regulate gene activation, so it was considered as a promising epigenetic target in anti-cancer drug development. Despite many inhibitors having been dis...

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Detalles Bibliográficos
Autores principales: Song, Lingyu, Cao, Jiawen, Chen, Lin, Du, Zhiyan, Zhang, Naixia, Cao, Danyan, Xiong, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10583817/
https://www.ncbi.nlm.nih.gov/pubmed/37859722
http://dx.doi.org/10.1039/d3md00288h

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10583817/
https://www.ncbi.nlm.nih.gov/pubmed/37859722
http://dx.doi.org/10.1039/d3md00288h

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