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Genetic analysis of African swine fever viruses based on E183L (p54) gene, circulating in South Sumatra and Lampung province, Indonesia

BACKGROUND AND AIM: African swine fever (ASF) is a disease that emerged in Indonesia in 2019 in the North Sumatra province and spread rapidly to other areas, such as South Sumatra and Lampung, in 2020. This study aimed to identify the phylogenetics of the ASF virus (ASFV) in the provinces of South S...

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Autores principales: Anggy, Fransiska Panasea, Nugroho, Widagdo Sri, Irianingsih, Sri Handayani, Enny, Saswiyanti, Srihanto, Eko Agus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Veterinary World 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10583869/
https://www.ncbi.nlm.nih.gov/pubmed/37859961
http://dx.doi.org/10.14202/vetworld.2023.1985-1990
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author Anggy, Fransiska Panasea
Nugroho, Widagdo Sri
Irianingsih, Sri Handayani
Enny, Saswiyanti
Srihanto, Eko Agus
author_facet Anggy, Fransiska Panasea
Nugroho, Widagdo Sri
Irianingsih, Sri Handayani
Enny, Saswiyanti
Srihanto, Eko Agus
author_sort Anggy, Fransiska Panasea
collection PubMed
description BACKGROUND AND AIM: African swine fever (ASF) is a disease that emerged in Indonesia in 2019 in the North Sumatra province and spread rapidly to other areas, such as South Sumatra and Lampung, in 2020. This study aimed to identify the phylogenetics of the ASF virus (ASFV) in the provinces of South Sumatra and Lampung. MATERIALS AND METHODS: Nine ASFV isolates collected from the Disease Investigation Center in Lampung were used in this study. The isolates were from ASF cases in South Sumatra and Lampung in 2020–2022. The isolates were sequenced and compared with other ASFV isolates to establish the virus genotype. Sequencing was performed using the complete E183L gene target encoding the p54 protein. RESULTS: This study showed that ASFV from South Sumatera and Lampung Province belongs to genotype II. CONCLUSION: Based on the analysis of the E183L gene, all nine ASFV isolates that originated from South Sumatra and Lampung were identical to other genotype II ASFV isolates from Georgia, China, Vietnam, and Timor Leste.
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spelling pubmed-105838692023-10-19 Genetic analysis of African swine fever viruses based on E183L (p54) gene, circulating in South Sumatra and Lampung province, Indonesia Anggy, Fransiska Panasea Nugroho, Widagdo Sri Irianingsih, Sri Handayani Enny, Saswiyanti Srihanto, Eko Agus Vet World Research Article BACKGROUND AND AIM: African swine fever (ASF) is a disease that emerged in Indonesia in 2019 in the North Sumatra province and spread rapidly to other areas, such as South Sumatra and Lampung, in 2020. This study aimed to identify the phylogenetics of the ASF virus (ASFV) in the provinces of South Sumatra and Lampung. MATERIALS AND METHODS: Nine ASFV isolates collected from the Disease Investigation Center in Lampung were used in this study. The isolates were from ASF cases in South Sumatra and Lampung in 2020–2022. The isolates were sequenced and compared with other ASFV isolates to establish the virus genotype. Sequencing was performed using the complete E183L gene target encoding the p54 protein. RESULTS: This study showed that ASFV from South Sumatera and Lampung Province belongs to genotype II. CONCLUSION: Based on the analysis of the E183L gene, all nine ASFV isolates that originated from South Sumatra and Lampung were identical to other genotype II ASFV isolates from Georgia, China, Vietnam, and Timor Leste. Veterinary World 2023-09 2023-09-23 /pmc/articles/PMC10583869/ /pubmed/37859961 http://dx.doi.org/10.14202/vetworld.2023.1985-1990 Text en Copyright: © Anggy, et al. https://creativecommons.org/licenses/by/4.0/Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Anggy, Fransiska Panasea
Nugroho, Widagdo Sri
Irianingsih, Sri Handayani
Enny, Saswiyanti
Srihanto, Eko Agus
Genetic analysis of African swine fever viruses based on E183L (p54) gene, circulating in South Sumatra and Lampung province, Indonesia
title Genetic analysis of African swine fever viruses based on E183L (p54) gene, circulating in South Sumatra and Lampung province, Indonesia
title_full Genetic analysis of African swine fever viruses based on E183L (p54) gene, circulating in South Sumatra and Lampung province, Indonesia
title_fullStr Genetic analysis of African swine fever viruses based on E183L (p54) gene, circulating in South Sumatra and Lampung province, Indonesia
title_full_unstemmed Genetic analysis of African swine fever viruses based on E183L (p54) gene, circulating in South Sumatra and Lampung province, Indonesia
title_short Genetic analysis of African swine fever viruses based on E183L (p54) gene, circulating in South Sumatra and Lampung province, Indonesia
title_sort genetic analysis of african swine fever viruses based on e183l (p54) gene, circulating in south sumatra and lampung province, indonesia
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10583869/
https://www.ncbi.nlm.nih.gov/pubmed/37859961
http://dx.doi.org/10.14202/vetworld.2023.1985-1990
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