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The role of miRNAs in Behçet’s disease

The symptoms of Behçet’s disease (BD), a multisystemic condition with autoimmune and inflammation as hallmarks, include arthritis, recurring oral and vaginal ulcers, skin rashes and lesions, and involvement of the nervous, gastrointestinal, and vascular systems. Non-coding RNAs (ncRNAs), including m...

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Autores principales: Gu, Feihan, Huang, Xu, Huang, Wenkai, Zhao, Mingyu, Zheng, Hu, Wang, Yuanyin, Chen, Ran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10584330/
https://www.ncbi.nlm.nih.gov/pubmed/37860009
http://dx.doi.org/10.3389/fimmu.2023.1249826
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author Gu, Feihan
Huang, Xu
Huang, Wenkai
Zhao, Mingyu
Zheng, Hu
Wang, Yuanyin
Chen, Ran
author_facet Gu, Feihan
Huang, Xu
Huang, Wenkai
Zhao, Mingyu
Zheng, Hu
Wang, Yuanyin
Chen, Ran
author_sort Gu, Feihan
collection PubMed
description The symptoms of Behçet’s disease (BD), a multisystemic condition with autoimmune and inflammation as hallmarks, include arthritis, recurring oral and vaginal ulcers, skin rashes and lesions, and involvement of the nervous, gastrointestinal, and vascular systems. Non-coding RNAs (ncRNAs), including microRNAs (miRNAs), long non-coding RNAs (lncRNAs), and circular RNAs (circRNAs), may be important regulators of inflammation and autoimmune disease. These ncRNAs are essential to the physiological and pathophysiological disease course, and miRNA in particular has received significant attention for its role and function in BD and its potential use as a diagnostic biomarker in recent years. Although promising as therapeutic targets, miRNAs must be studied further to fully comprehend how miRNAs in BD act biologically.
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spelling pubmed-105843302023-10-19 The role of miRNAs in Behçet’s disease Gu, Feihan Huang, Xu Huang, Wenkai Zhao, Mingyu Zheng, Hu Wang, Yuanyin Chen, Ran Front Immunol Immunology The symptoms of Behçet’s disease (BD), a multisystemic condition with autoimmune and inflammation as hallmarks, include arthritis, recurring oral and vaginal ulcers, skin rashes and lesions, and involvement of the nervous, gastrointestinal, and vascular systems. Non-coding RNAs (ncRNAs), including microRNAs (miRNAs), long non-coding RNAs (lncRNAs), and circular RNAs (circRNAs), may be important regulators of inflammation and autoimmune disease. These ncRNAs are essential to the physiological and pathophysiological disease course, and miRNA in particular has received significant attention for its role and function in BD and its potential use as a diagnostic biomarker in recent years. Although promising as therapeutic targets, miRNAs must be studied further to fully comprehend how miRNAs in BD act biologically. Frontiers Media S.A. 2023-10-04 /pmc/articles/PMC10584330/ /pubmed/37860009 http://dx.doi.org/10.3389/fimmu.2023.1249826 Text en Copyright © 2023 Gu, Huang, Huang, Zhao, Zheng, Wang and Chen https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Immunology
Gu, Feihan
Huang, Xu
Huang, Wenkai
Zhao, Mingyu
Zheng, Hu
Wang, Yuanyin
Chen, Ran
The role of miRNAs in Behçet’s disease
title The role of miRNAs in Behçet’s disease
title_full The role of miRNAs in Behçet’s disease
title_fullStr The role of miRNAs in Behçet’s disease
title_full_unstemmed The role of miRNAs in Behçet’s disease
title_short The role of miRNAs in Behçet’s disease
title_sort role of mirnas in behçet’s disease
topic Immunology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10584330/
https://www.ncbi.nlm.nih.gov/pubmed/37860009
http://dx.doi.org/10.3389/fimmu.2023.1249826
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