CD73 controls Myosin II–driven invasion, metastasis, and immunosuppression in amoeboid pancreatic cancer cells

Pancreatic ductal adenocarcinoma (PDAC) has a very poor prognosis because of its high propensity to metastasize and its immunosuppressive microenvironment. Using a panel of pancreatic cancer cell lines, three-dimensional (3D) invasion systems, microarray gene signatures, microfluidic devices, mouse...

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Detalles Bibliográficos
Autores principales: Samain, Remi, Maiques, Oscar, Monger, Joanne, Lam, Hoyin, Candido, Juliana, George, Samantha, Ferrari, Nicola, KohIhammer, Leonie, Lunetto, Sophia, Varela, Adrian, Orgaz, Jose L., Vilardell, Felip, Olsina, Jorge Juan, Matias-Guiu, Xavier, Sarker, Debashis, Biddle, Adrian, Balkwill, Frances R., Eyles, Jim, Wilkinson, Robert W., Kocher, Hemant M., Calvo, Fernando, Wells, Claire M., Sanz-Moreno, Victoria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10584351/
https://www.ncbi.nlm.nih.gov/pubmed/37851808
http://dx.doi.org/10.1126/sciadv.adi0244

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