SIRT-1 is required for release of enveloped enteroviruses

Enterovirus D68 (EV-D68) is a re-emerging enterovirus that causes acute respiratory illness in infants and has recently been linked to Acute Flaccid Myelitis. Here, we show that the histone deacetylase, SIRT-1, is essential for autophagy and EV-D68 infection. Knockdown of SIRT-1 inhibits autophagy a...

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Detalles Bibliográficos
Autores principales: Jassey, Alagie, Logue, James, Weston, Stuart, Wagner, Michael A, Galitska, Ganna, Miller, Katelyn, Frieman, Matthew, Jackson, William T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10584371/
https://www.ncbi.nlm.nih.gov/pubmed/37850626
http://dx.doi.org/10.7554/eLife.87993

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