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Clinical utility of polygenic scores for cardiometabolic disease in Arabs

Arabs account for 5% of the world population and have a high burden of cardiometabolic disease, yet clinical utility of polygenic risk prediction in Arabs remains understudied. Among 5399 Arab patients, we optimize polygenic scores for 10 cardiometabolic traits, achieving a performance that is bette...

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Detalles Bibliográficos
Autores principales:	Shim, Injeong, Kuwahara, Hiroyuki, Chen, NingNing, Hashem, Mais O., AlAbdi, Lama, Abouelhoda, Mohamed, Won, Hong-Hee, Natarajan, Pradeep, Ellinor, Patrick T., Khera, Amit V., Gao, Xin, Alkuraya, Fowzan S., Fahed, Akl C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10584889/ https://www.ncbi.nlm.nih.gov/pubmed/37852978 http://dx.doi.org/10.1038/s41467-023-41985-1

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