MacroH2A1.1 as a crossroad between epigenetics, inflammation and metabolism of mesenchymal stromal cells in myelodysplastic syndromes

Ineffective hematopoiesis is a hallmark of myelodysplastic syndromes (MDS). Hematopoietic alterations in MDS patients strictly correlate with microenvironment dysfunctions, eventually affecting also the mesenchymal stromal cell (MSC) compartment. Stromal cells are indeed epigenetically reprogrammed...

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Detalles Bibliográficos
Autores principales: Giallongo, C., Dulcamare, I., Giallongo, S., Duminuco, A., Pieragostino, D., Cufaro, M. C., Amorini, A. M., Lazzarino, G., Romano, A., Parrinello, N., Di Rosa, M., Broggi, G., Caltabiano, R., Caraglia, M., Scrima, M., Pasquale, L. S., Tathode, M. S., Li Volti, G., Motterlini, R., Di Raimondo, F., Tibullo, D., Palumbo, G. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10584900/
https://www.ncbi.nlm.nih.gov/pubmed/37852977
http://dx.doi.org/10.1038/s41419-023-06197-x

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