The SMN complex drives structural changes in human snRNAs to enable snRNP assembly

Spliceosomal snRNPs are multicomponent particles that undergo a complex maturation pathway. Human Sm-class snRNAs are generated as 3′-end extended precursors, which are exported to the cytoplasm and assembled together with Sm proteins into core RNPs by the SMN complex. Here, we provide evidence that...

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Detalles Bibliográficos
Autores principales: Pánek, Josef, Roithová, Adriana, Radivojević, Nenad, Sýkora, Michal, Prusty, Archana Bairavasundaram, Huston, Nicholas, Wan, Han, Pyle, Anna Marie, Fischer, Utz, Staněk, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10584915/
https://www.ncbi.nlm.nih.gov/pubmed/37852981
http://dx.doi.org/10.1038/s41467-023-42324-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10584915/
https://www.ncbi.nlm.nih.gov/pubmed/37852981
http://dx.doi.org/10.1038/s41467-023-42324-0

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