Cargando…
Direct regulation of the voltage sensor of HCN channels by membrane lipid compartmentalization
Ion channels function within a membrane environment characterized by dynamic lipid compartmentalization. Limited knowledge exists regarding the response of voltage-gated ion channels to transmembrane potential within distinct membrane compartments. By leveraging fluorescence lifetime imaging microsc...
Autores principales: | Handlin, Lucas J., Dai, Gucan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10584925/ https://www.ncbi.nlm.nih.gov/pubmed/37852983 http://dx.doi.org/10.1038/s41467-023-42363-7 |
Ejemplares similares
-
The HCN Channel Voltage Sensor Undergoes A Large Downward Motion During Hyperpolarization
por: Dai, Gucan, et al.
Publicado: (2019) -
Electromechanical coupling mechanism for activation and inactivation of an HCN channel
por: Dai, Gucan, et al.
Publicado: (2021) -
Kinetic Relationship between the Voltage Sensor and the Activation Gate in spHCN Channels
por: Bruening-Wright, Andrew, et al.
Publicado: (2007) -
Voltage Sensor Movement and cAMP Binding Allosterically Regulate an Inherently Voltage-independent Closed−Open Transition in HCN Channels
por: Chen, Shan, et al.
Publicado: (2007) -
Integrated Allosteric Model of Voltage Gating of Hcn Channels
por: Altomare, Claudia, et al.
Publicado: (2001)