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Statin-Associated Autoimmune Myopathy Masquerading As Recurrent Falls in an Older Adult
Statins are widely prescribed in clinical practice. Statin-induced myopathy is relatively common, benign, and resolves after statin withdrawal. However, statin-associated autoimmune myopathy is an exceptionally rare and devastating complication that can occur any time after statin initiation. It is...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10585192/ https://www.ncbi.nlm.nih.gov/pubmed/37868542 http://dx.doi.org/10.7759/cureus.45515 |
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author | Suppamutharwyam, Malarkodi Shah, Tunku Muzafar |
author_facet | Suppamutharwyam, Malarkodi Shah, Tunku Muzafar |
author_sort | Suppamutharwyam, Malarkodi |
collection | PubMed |
description | Statins are widely prescribed in clinical practice. Statin-induced myopathy is relatively common, benign, and resolves after statin withdrawal. However, statin-associated autoimmune myopathy is an exceptionally rare and devastating complication that can occur any time after statin initiation. It is characterized by persistent muscle weakness and elevated creatine kinase levels that persist after statin withdrawal. Herein, we present a challenging case of a statin-associated autoimmune myopathy that developed after a decade of atorvastatin use that resulted in debilitating weakness. It is important to recognize cases of myopathies wherein statin discontinuation and aggressive immunosuppressive therapy can reduce morbidity and mortality. |
format | Online Article Text |
id | pubmed-10585192 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-105851922023-10-20 Statin-Associated Autoimmune Myopathy Masquerading As Recurrent Falls in an Older Adult Suppamutharwyam, Malarkodi Shah, Tunku Muzafar Cureus Geriatrics Statins are widely prescribed in clinical practice. Statin-induced myopathy is relatively common, benign, and resolves after statin withdrawal. However, statin-associated autoimmune myopathy is an exceptionally rare and devastating complication that can occur any time after statin initiation. It is characterized by persistent muscle weakness and elevated creatine kinase levels that persist after statin withdrawal. Herein, we present a challenging case of a statin-associated autoimmune myopathy that developed after a decade of atorvastatin use that resulted in debilitating weakness. It is important to recognize cases of myopathies wherein statin discontinuation and aggressive immunosuppressive therapy can reduce morbidity and mortality. Cureus 2023-09-18 /pmc/articles/PMC10585192/ /pubmed/37868542 http://dx.doi.org/10.7759/cureus.45515 Text en Copyright © 2023, Suppamutharwyam et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Geriatrics Suppamutharwyam, Malarkodi Shah, Tunku Muzafar Statin-Associated Autoimmune Myopathy Masquerading As Recurrent Falls in an Older Adult |
title | Statin-Associated Autoimmune Myopathy Masquerading As Recurrent Falls in an Older Adult |
title_full | Statin-Associated Autoimmune Myopathy Masquerading As Recurrent Falls in an Older Adult |
title_fullStr | Statin-Associated Autoimmune Myopathy Masquerading As Recurrent Falls in an Older Adult |
title_full_unstemmed | Statin-Associated Autoimmune Myopathy Masquerading As Recurrent Falls in an Older Adult |
title_short | Statin-Associated Autoimmune Myopathy Masquerading As Recurrent Falls in an Older Adult |
title_sort | statin-associated autoimmune myopathy masquerading as recurrent falls in an older adult |
topic | Geriatrics |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10585192/ https://www.ncbi.nlm.nih.gov/pubmed/37868542 http://dx.doi.org/10.7759/cureus.45515 |
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