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Statin-Associated Autoimmune Myopathy Masquerading As Recurrent Falls in an Older Adult

Statins are widely prescribed in clinical practice. Statin-induced myopathy is relatively common, benign, and resolves after statin withdrawal. However, statin-associated autoimmune myopathy is an exceptionally rare and devastating complication that can occur any time after statin initiation. It is...

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Autores principales: Suppamutharwyam, Malarkodi, Shah, Tunku Muzafar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10585192/
https://www.ncbi.nlm.nih.gov/pubmed/37868542
http://dx.doi.org/10.7759/cureus.45515
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author Suppamutharwyam, Malarkodi
Shah, Tunku Muzafar
author_facet Suppamutharwyam, Malarkodi
Shah, Tunku Muzafar
author_sort Suppamutharwyam, Malarkodi
collection PubMed
description Statins are widely prescribed in clinical practice. Statin-induced myopathy is relatively common, benign, and resolves after statin withdrawal. However, statin-associated autoimmune myopathy is an exceptionally rare and devastating complication that can occur any time after statin initiation. It is characterized by persistent muscle weakness and elevated creatine kinase levels that persist after statin withdrawal. Herein, we present a challenging case of a statin-associated autoimmune myopathy that developed after a decade of atorvastatin use that resulted in debilitating weakness. It is important to recognize cases of myopathies wherein statin discontinuation and aggressive immunosuppressive therapy can reduce morbidity and mortality.
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spelling pubmed-105851922023-10-20 Statin-Associated Autoimmune Myopathy Masquerading As Recurrent Falls in an Older Adult Suppamutharwyam, Malarkodi Shah, Tunku Muzafar Cureus Geriatrics Statins are widely prescribed in clinical practice. Statin-induced myopathy is relatively common, benign, and resolves after statin withdrawal. However, statin-associated autoimmune myopathy is an exceptionally rare and devastating complication that can occur any time after statin initiation. It is characterized by persistent muscle weakness and elevated creatine kinase levels that persist after statin withdrawal. Herein, we present a challenging case of a statin-associated autoimmune myopathy that developed after a decade of atorvastatin use that resulted in debilitating weakness. It is important to recognize cases of myopathies wherein statin discontinuation and aggressive immunosuppressive therapy can reduce morbidity and mortality. Cureus 2023-09-18 /pmc/articles/PMC10585192/ /pubmed/37868542 http://dx.doi.org/10.7759/cureus.45515 Text en Copyright © 2023, Suppamutharwyam et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Geriatrics
Suppamutharwyam, Malarkodi
Shah, Tunku Muzafar
Statin-Associated Autoimmune Myopathy Masquerading As Recurrent Falls in an Older Adult
title Statin-Associated Autoimmune Myopathy Masquerading As Recurrent Falls in an Older Adult
title_full Statin-Associated Autoimmune Myopathy Masquerading As Recurrent Falls in an Older Adult
title_fullStr Statin-Associated Autoimmune Myopathy Masquerading As Recurrent Falls in an Older Adult
title_full_unstemmed Statin-Associated Autoimmune Myopathy Masquerading As Recurrent Falls in an Older Adult
title_short Statin-Associated Autoimmune Myopathy Masquerading As Recurrent Falls in an Older Adult
title_sort statin-associated autoimmune myopathy masquerading as recurrent falls in an older adult
topic Geriatrics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10585192/
https://www.ncbi.nlm.nih.gov/pubmed/37868542
http://dx.doi.org/10.7759/cureus.45515
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