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Histopathology of fused triplet placenta in rat

A fused triplet placenta was observed in a Wistar Hannover rat on gestation day 15. Each placenta (referred to as PL-A, PL-B, and PL-C) of this fused placenta was attached to one fetus each, but their fetal weights were lower than that of the fetus attached to the only normal placenta (referred to a...

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Autores principales: Furukawa, Satoshi, Tsuji, Naho, Hayashi, Seigo, Kuroda, Yusuke, Kimura, Masayuki, Kojima, Chisato, Takeuchi, Kazuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society of Toxicologic Pathology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10585243/
https://www.ncbi.nlm.nih.gov/pubmed/37868115
http://dx.doi.org/10.1293/tox.2023-0026
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author Furukawa, Satoshi
Tsuji, Naho
Hayashi, Seigo
Kuroda, Yusuke
Kimura, Masayuki
Kojima, Chisato
Takeuchi, Kazuya
author_facet Furukawa, Satoshi
Tsuji, Naho
Hayashi, Seigo
Kuroda, Yusuke
Kimura, Masayuki
Kojima, Chisato
Takeuchi, Kazuya
author_sort Furukawa, Satoshi
collection PubMed
description A fused triplet placenta was observed in a Wistar Hannover rat on gestation day 15. Each placenta (referred to as PL-A, PL-B, and PL-C) of this fused placenta was attached to one fetus each, but their fetal weights were lower than that of the fetus attached to the only normal placenta (referred to as PL-N) in this dam. Histopathologically, thinning of the trophoblastic septa and dilatation of the maternal sinusoid in the labyrinth zone were observed in PL-B and PL-C, but not in PL-A or PL-N. The points of placental fusion were at the junctional zone derived from each side of the placenta without connective tissues, and the septum was composed of trophoblastic giant cells. Although PL-A had a solitary metrial gland, PL-B and PL-C shared one metrial gland with one spiral artery terminus branching towards each labyrinth zone.
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spelling pubmed-105852432023-10-20 Histopathology of fused triplet placenta in rat Furukawa, Satoshi Tsuji, Naho Hayashi, Seigo Kuroda, Yusuke Kimura, Masayuki Kojima, Chisato Takeuchi, Kazuya J Toxicol Pathol Case Report A fused triplet placenta was observed in a Wistar Hannover rat on gestation day 15. Each placenta (referred to as PL-A, PL-B, and PL-C) of this fused placenta was attached to one fetus each, but their fetal weights were lower than that of the fetus attached to the only normal placenta (referred to as PL-N) in this dam. Histopathologically, thinning of the trophoblastic septa and dilatation of the maternal sinusoid in the labyrinth zone were observed in PL-B and PL-C, but not in PL-A or PL-N. The points of placental fusion were at the junctional zone derived from each side of the placenta without connective tissues, and the septum was composed of trophoblastic giant cells. Although PL-A had a solitary metrial gland, PL-B and PL-C shared one metrial gland with one spiral artery terminus branching towards each labyrinth zone. Japanese Society of Toxicologic Pathology 2023-06-05 2023-10 /pmc/articles/PMC10585243/ /pubmed/37868115 http://dx.doi.org/10.1293/tox.2023-0026 Text en ©2023 The Japanese Society of Toxicologic Pathology https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License. (CC-BY-NC-ND 4.0: https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Furukawa, Satoshi
Tsuji, Naho
Hayashi, Seigo
Kuroda, Yusuke
Kimura, Masayuki
Kojima, Chisato
Takeuchi, Kazuya
Histopathology of fused triplet placenta in rat
title Histopathology of fused triplet placenta in rat
title_full Histopathology of fused triplet placenta in rat
title_fullStr Histopathology of fused triplet placenta in rat
title_full_unstemmed Histopathology of fused triplet placenta in rat
title_short Histopathology of fused triplet placenta in rat
title_sort histopathology of fused triplet placenta in rat
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10585243/
https://www.ncbi.nlm.nih.gov/pubmed/37868115
http://dx.doi.org/10.1293/tox.2023-0026
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