Steatosis drives monocyte-derived macrophage accumulation in human metabolic dysfunction-associated fatty liver disease

BACKGROUND & AIMS: Metabolic dysfunction-associated fatty liver disease (MAFLD) is a common complication of obesity with a hallmark feature of hepatic steatosis. Recent data from animal models of MAFLD have demonstrated substantial changes in macrophage composition in the fatty liver. In humans,...

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Detalles Bibliográficos
Autores principales: Chan, Mandy M., Daemen, Sabine, Beals, Joseph W., Terekhova, Marina, Yang, Bin Q., Fu, Christina F., He, Li, Park, Arick C., Smith, Gordon I., Razani, Babak, Byrnes, Kathleen, Beatty, Wandy L., Eckhouse, Shaina R., Eagon, J. Christopher, Ferguson, Daniel, Finck, Brian N., Klein, Samuel, Artyomov, Maxim N., Schilling, Joel D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10585307/
https://www.ncbi.nlm.nih.gov/pubmed/37869071
http://dx.doi.org/10.1016/j.jhepr.2023.100877

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