AIM2 promotes T(H)17 cells differentiation by regulating RORγt transcription activity

AIM2 is an interferon-inducible HIN-200 protein family member and is well-documented for its roles in innate immune responses as a DNA sensor. Recent studies have highlighted AIM2’s function on regulatory T cells (Treg) and follicular T cells (Tfh). However, its involvement in Th17 cell differentiat...

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Detalles Bibliográficos
Autores principales: Leite, Jefferson Antônio, Menezes, Luísa, Martins, Eloisa, Rodrigues, Tamara Silva, Tavares, Lucas, Ebering, Anna, Schelmbauer, Carsten, Martelossi Cebinelli, Guilherme C., Zinina, Valeriya, Golden, Artemiy, Soshnikova, Natalia, Zamboni, Dario S., Cunha, Fernando Q., Huber, Magdalena, Silva, João Santana, Waisman, Ari, Carlos, Daniela, Saraiva Câmara, Niels Olsen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10585393/
https://www.ncbi.nlm.nih.gov/pubmed/37867943
http://dx.doi.org/10.1016/j.isci.2023.108134

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