Modification of lysine-260 2-hydroxyisobutyrylation destabilizes ALDH1A1 expression to regulate bladder cancer progression

ALDH1A1 is one of the classical stem cell markers for bladder cancer. Lysine 2-hydroxyisobutyrylation (Khib) is a newfound modification to modulate the protein expression, and the underlying mechanisms of how ALDH1A1 was regulated by Khib modification in bladder cancer remains unknown. Here, ALDH1A1...

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Detalles Bibliográficos
Autores principales: Zhang, Zhilei, Wang, Yonghua, Liang, Zhijuan, Meng, Zhaoyuan, Zhang, Xiangyan, Ma, Guofeng, Chen, Yuanbin, Zhang, Mingxin, Su, Yinjie, Li, Zhiqiang, Liang, Ye, Niu, Haitao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10585400/
https://www.ncbi.nlm.nih.gov/pubmed/37867947
http://dx.doi.org/10.1016/j.isci.2023.108142

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