Cargando…

Genetic Variation and Sickle Cell Disease Severity: A Systematic Review and Meta-Analysis

IMPORTANCE: Sickle cell disease (SCD) is a monogenic disorder, yet clinical outcomes are influenced by additional genetic factors. Despite decades of research, the genetics of SCD remain poorly understood. OBJECTIVE: To assess all reported genetic modifiers of SCD, evaluate the design of associated...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kirkham, Justin K., Estepp, Jeremie H., Weiss, Mitch J., Rashkin, Sara R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Medical Association 2023
Materias:	Original Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10585422/ https://www.ncbi.nlm.nih.gov/pubmed/37851445 http://dx.doi.org/10.1001/jamanetworkopen.2023.37484

Ejemplares similares

Leveraging mathematical modeling to analyze nonadherence for hydroxyurea therapy in sickle cell disease
por: Pandey, Akancha, et al.
Publicado: (2023)

Mathematical Modeling of Hydroxyurea Therapy in Individuals with Sickle Cell Disease
por: Pandey, Akancha, et al.
Publicado: (2022)

Left Ventricular Rotational Mechanics in Tanzanian Children with Sickle Cell Disease
por: Di Maria, Michael V., et al.
Publicado: (2015)

Brain Volumes and Cognition in Patients with Sickle Cell Anaemia: A Systematic Review and Meta-Analysis
por: Hamdule, Shifa, et al.
Publicado: (2023)

Neuroimaging and Cognitive Function in Sickle Cell Disease: A Systematic Review
por: Abdi, Suad S., et al.
Publicado: (2023)

Genetic Basis of Variation in Heat and Ethanol Tolerance in Saccharomyces cerevisiae
por: Riles, Linda, et al.
Publicado: (2018)

The quantitative genetics of the prevalence of infectious diseases: hidden genetic variation due to indirect genetic effects dominates heritable variation and response to selection
por: Bijma, Piter, et al.
Publicado: (2021)

Genetic Variation for Life History Sensitivity to Seasonal Warming in Arabidopsis thaliana
por: Li, Yan, et al.
Publicado: (2014)

Severe Maternal Morbidity and Mortality in Sickle Cell Disease in the National Inpatient Sample, 2012-2018
por: Early, Macy L., et al.
Publicado: (2023)

Natural Genetic Variation for Growth and Development Revealed by High-Throughput Phenotyping in Arabidopsis thaliana
por: Zhang, Xu, et al.
Publicado: (2012)

Estimated Life Expectancy and Income of Patients With Sickle Cell Disease Compared With Those Without Sickle Cell Disease
por: Lubeck, Deborah, et al.
Publicado: (2019)

Association of Mindfulness-Based Interventions With Anxiety Severity in Adults With Cancer: A Systematic Review and Meta-analysis
por: Oberoi, Sapna, et al.
Publicado: (2020)

The Genetic Basis of Mutation Rate Variation in Yeast
por: Gou, Liangke, et al.
Publicado: (2019)

Use of Disease-Modifying Treatments in Patients With Sickle Cell Disease
por: Newman, Terri Victoria, et al.
Publicado: (2023)

Implications of Host Genetic Variation on the Risk and Prevalence of Infectious Diseases Transmitted Through the Environment
por: Doeschl-Wilson, Andrea B., et al.
Publicado: (2011)

Comparisons of Severe Maternal Morbidity and Other Adverse Pregnancy Outcomes in Pregnant People With Sickle Cell Disease vs Anemia
por: Early, Macy L., et al.
Publicado: (2023)

Variations in Guidelines for Diagnosis of Child Physical Abuse in High-Income Countries: A Systematic Review
por: Blangis, Flora, et al.
Publicado: (2021)

Epidemiology of Stroke in Sickle Cell Disease
por: Kirkham, Fenella Jane, et al.
Publicado: (2021)

Genetic Architecture of Flowering-Time Variation in Arabidopsis thaliana
por: Salomé, Patrice A., et al.
Publicado: (2011)

Genetic Variation and the Fate of Beneficial Mutations in Asexual Populations
por: Lang, Gregory I., et al.
Publicado: (2011)

Genetic Variation in the Chemical Components of Eucalyptus globulus Wood
por: Stackpole, Desmond J., et al.
Publicado: (2011)

The Genetic Basis of Baculum Size and Shape Variation in Mice
por: Schultz, Nicholas G., et al.
Publicado: (2016)

Regional Variation in Genetic Control of Atherosclerosis in Hyperlipidemic Mice
por: Jones, Michael B., et al.
Publicado: (2020)

App-Based Interventions for Moderate to Severe Depression: A Systematic Review and Meta-Analysis
por: Bae, Hayoung, et al.
Publicado: (2023)

Sickle cell disease, sickle trait and the risk for venous thromboembolism: a systematic review and meta-analysis
por: Noubiap, Jean Jacques, et al.
Publicado: (2018)

Prehabilitation for Patients Undergoing Orthopedic Surgery: A Systematic Review and Meta-analysis
por: Punnoose, Anuj, et al.
Publicado: (2023)

Genetic Mapping of Natural Variation in Schooling Tendency in the Threespine Stickleback
por: Greenwood, Anna K., et al.
Publicado: (2015)

Forward Genetics by Sequencing EMS Variation-Induced Inbred Lines
por: Addo-Quaye, Charles, et al.
Publicado: (2016)

The Genetic Basis of Natural Variation in Caenorhabditis elegans Telomere Length
por: Cook, Daniel E., et al.
Publicado: (2016)

Genetic Regulation of Transcriptional Variation in Natural Arabidopsis thaliana Accessions
por: Zan, Yanjun, et al.
Publicado: (2016)

Variation in Recombination Rate and Its Genetic Determinism in Sheep Populations
por: Petit, Morgane, et al.
Publicado: (2017)

Natural Genetic Variation in the Caenorhabditis elegans Response to Pseudomonas aeruginosa
por: Martin, Natalia, et al.
Publicado: (2017)

Genetic Basis of Natural Variation in Spontaneous Grooming in Drosophila melanogaster
por: Yanagawa, Aya, et al.
Publicado: (2020)

High bias and low precision for estimated versus measured glomerular filtration rate in pediatric sickle cell anemia
por: Lebensburger, Jeffrey D., et al.
Publicado: (2020)

Impact of Genetic Variations on Thromboembolic Risk in Saudis with Sickle Cell Disease
por: Alshabeeb, Mohammad A., et al.
Publicado: (2023)

The non‐genetic paternal factors for congenital heart defects: A systematic review and meta‐analysis
por: Peng, Jiayu, et al.
Publicado: (2019)

Cryptic genetic variation of expression quantitative trait locus architecture revealed by genetic perturbation in Caenorhabditis elegans
por: van Wijk, Marijke H, et al.
Publicado: (2023)

Perceptions of US Adolescents and Adults With Sickle Cell Disease on Their Quality of Care
por: Kanter, Julie, et al.
Publicado: (2020)

Examining Mental Health, Education, Employment, and Pain in Sickle Cell Disease
por: Harris, Kelly M., et al.
Publicado: (2023)

Genetic Architecture of Variation in the Lateral Line Sensory System of Threespine Sticklebacks
por: Wark, Abigail R., et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_qjr4op4dk661ir97oq8bqghbem