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Deciphering the decisive factors driving fate bifurcations in somatic cell reprogramming

Single-cell studies have demonstrated that somatic cell reprogramming is a continuous process of cell fates transition. Only partial reprogramming intermediates can overcome the molecular bottlenecks to acquire pluripotency. To decipher the underlying decisive factors driving cell fate, we identifie...

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Detalles Bibliográficos
Autores principales: Long, Chunshen, Li, Hanshuang, Liang, Pengfei, Chao, Lemuge, Hong, Yan, Zhang, Junping, Xi, Qilemuge, Zuo, Yongchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10585637/
https://www.ncbi.nlm.nih.gov/pubmed/37869261
http://dx.doi.org/10.1016/j.omtn.2023.102044