BRAF D594A mutation defines a unique biological and immuno-modulatory subgroup associated with functional CD8(+) T cell infiltration in colorectal cancer

BACKGROUND: BRAF non-V600 mutation occupies a relatively small but critical subset in colorectal cancer (CRC). However, little is known about the biological functions and impacts of BRAF class III mutation in CRC. Here, we aim to explore how D594A mutation impacts on biological behaviors and immune...

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Detalles Bibliográficos
Autores principales: Li, Wenjing, Zhao, Chenyi, Li, Wenhui, Gong, Yang, Ma, Kaili, Lu, Yujie, Liu, Xiaowei, Zhang, Lianjun, Guo, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10585750/
https://www.ncbi.nlm.nih.gov/pubmed/37853469
http://dx.doi.org/10.1186/s12967-023-04606-5

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